Who are the Okinawans? Ancestry, genome diversity, and implications for the genetic study of human longevity from a geographically isolated population (Q34736008)

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English	Who are the Okinawans? Ancestry, genome diversity, and implications for the genetic study of human longevity from a geographically isolated population	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 August 2017

Who are the Okinawans? Ancestry, genome diversity, and implications for the genetic study of human longevity from a geographically isolated population (English)

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4 August 2017

geographic isolation

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based on heuristic

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Caroline M Nievergelt

5

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1 June 2020

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Nasrine Bendjilali

1

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1 June 2020

Wen-Chi Hsueh

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1 June 2020

Qimei He

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1 June 2020

D Craig Willcox

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1 June 2020

Timothy A Donlon

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1 June 2020

Pui-Yan Kwok

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1 June 2020

Makoto Suzuki

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1 June 2020

Bradley J Willcox

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1 June 2020

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20 January 2014

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4 August 2017

The Journals of Gerontology

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1 June 2020

69

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1 June 2020

12

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1 June 2020

1474-1484

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1 June 2020

Inference of human continental origin and admixture proportions using a highly discriminative ancestry informative 41-SNP panel

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7 July 2018

Association analyses of insulin signaling pathway gene polymorphisms with healthy aging and longevity in Americans of Japanese ancestry

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7 July 2018

Detection of ancestry informative HLA alleles confirms the admixed origins of Japanese population.

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7 July 2018

Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges

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7 July 2018

The epidemiology of longevity and exceptional survival

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7 July 2018

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

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7 July 2018

The genetics of extreme longevity: lessons from the new England centenarian study

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7 July 2018

The history of human populations in the Japanese Archipelago inferred from genome-wide SNP data with a special reference to the Ainu and the Ryukyuan populations.

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7 July 2018

Apolipoprotein E and familial longevity

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7 July 2018

Exome sequencing and the genetic basis of complex traits

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7 July 2018

The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals

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7 July 2018

Paleolithic Contingent in Modern Japanese: Estimation and Inference using Genome-wide Data

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7 July 2018

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7 July 2018

Genetic determinants of exceptional human longevity: insights from the Okinawa Centenarian Study

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7 July 2018

Discovery of functional gene variants associated with human longevity: opportunities and challenges

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

7 July 2018

Immunogenetics of ageing

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7 July 2018

Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans

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7 July 2018

Heritability analysis of life span in a semi-isolated population followed across four centuries reveals the presence of pleiotropy between life span and reproduction

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7 July 2018

HRAS1 and LASS1 with APOE are associated with human longevity and healthy aging

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7 July 2018

The genetics of ageing

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

7 July 2018

The Okinawan diet: health implications of a low-calorie, nutrient-dense, antioxidant-rich dietary pattern low in glycemic load

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7 July 2018

Heritability and demographic analyses in the large isolated population of Val Borbera suggest advantages in mapping complex traits genes

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7 July 2018

Finding the missing heritability of complex diseases

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7 July 2018

Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae

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7 July 2018

Association of FOXO3A variation with human longevity confirmed in German centenarians

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7 July 2018

A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

7 July 2018

Y chromosome evidence of earliest modern human settlement in East Asia and multiple origins of Tibetan and Japanese populations

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

7 July 2018

FOXO3A genotype is strongly associated with human longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

7 July 2018

Worldwide human relationships inferred from genome-wide patterns of variation

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7 July 2018

Caloric restriction, the traditional Okinawan diet, and healthy aging: the diet of the world's longest-lived people and its potential impact on morbidity and life span.

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7 July 2018

CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure

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7 July 2018

Standardized subsets of the HGDP-CEPH Human Genome Diversity Cell Line Panel, accounting for atypical and duplicated samples and pairs of close relatives.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

7 July 2018

A haplotype map of the human genome

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

7 July 2018

The International HapMap Project Web site

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7 July 2018

No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

7 July 2018

The Human Genome Diversity Project: past, present and future

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

7 July 2018

Mitochondrial genome variation in eastern Asia and the peopling of Japan

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7 July 2018

Clinical phenotype of families with longevity.

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7 July 2018

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7 July 2018

Unique lipoprotein phenotype and genotype associated with exceptional longevity

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7 July 2018

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7 July 2018

A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4.

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7 July 2018

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7 July 2018

Inference of population structure using multilocus genotype data

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7 July 2018

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7 July 2018

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7 July 2018

Y chromosomal DNA variation and the peopling of Japan

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7 July 2018

On the association of restriction fragment length polymorphisms across species boundaries

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7 July 2018

Effects of the APOE ε2 allele on mortality and cognitive function in the oldest old.

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26 October 2018

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26 October 2018

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26 October 2018

They really are that old: a validation study of centenarian prevalence in Okinawa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

26 October 2018

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1 reference

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26 October 2018

Siblings of Okinawan centenarians share lifelong mortality advantages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

26 October 2018

Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies

1 reference

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26 October 2018

The Human Genome Diversity Project: past, present and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

26 October 2018

Healthy life expectancy in 191 countries, 1999.

1 reference

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26 October 2018

Familial excess longevity in Utah genealogies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

26 October 2018

HLA-DR alleles display sex-dependent effects on survival and discriminate between individual and familial longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271021

26 October 2018

First Autopsy Study of an Okinawan Centenarian: Absence of Many Age-Related Diseases

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https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

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Evaluating potential for whole-genome studies in Kosrae, an isolated population in Micronesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The social gradient in life expectancy: the contrary case of Okinawa in Japan

1 reference

https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetic studies on DNA polymorphism of the HLA class II genes associated with human longevity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[The population history of the Japanese]

1 reference

https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of major histocompatibility complex region genes on human longevity among Okinawan-Japanese centenarians and nonagenarians

1 reference

https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

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[Chronological study concerning ADL among Okinawan centenarians]

1 reference

https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Siblings of centenarians live longer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Life at the extreme limit: phenotypic characteristics of supercentenarians in Okinawa

1 reference

https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

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[Medical researches upon centenarians in Okinawa (1)--Case controlled study of family history as hereditary influence on longevity]

1 reference

https://pubmed.ncbi.nlm.nih.gov/24444611

12 December 2020

based on heuristic

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genalex 6: genetic analysis in Excel. Population genetic software for teaching and research

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20 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1111/J.1471-8286.2005.01155.X

Identifiers

10.1093/GERONA/GLT203

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24444611%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PMC publication ID

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Europe PubMed Central

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1 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24444611%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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