Src SH2 arginine 175 is required for cell motility: specific focal adhesion kinase targeting and focal adhesion assembly function (Q34718178)

4 August 2017

title

Src SH2 arginine 175 is required for cell motility: specific focal adhesion kinase targeting and focal adhesion assembly function (English)

1 reference

4 August 2017

Myeong Gu Yeo

0 references

Michael A Partridge

1 reference

4 August 2017

Ellen J Ezratty

1 reference

4 August 2017

Qiong Shen

1 reference

4 August 2017

Gregg G Gundersen

1 reference

4 August 2017

Eugene E Marcantonio

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4 August 2017

language of work or name

English

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publication date

1 June 2006

1 reference

Molecular and Cellular Biology

4 August 2017

published in

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4 August 2017

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4 August 2017

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4 August 2017

page(s)

4399-4409

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describes a project that uses

4 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1489135/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Focal adhesion kinase: in command and control of cell motility

7 July 2018

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7 July 2018

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FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

7 July 2018

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RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages

7 July 2018

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7 July 2018

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7 July 2018

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SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading

7 July 2018

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7 July 2018

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7 July 2018

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Structural basis for specificity switching of the Src SH2 domain

7 July 2018

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A phosphotyrosine displacement mechanism for activation of Src by PTPalpha

7 July 2018

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Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src.

7 July 2018

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Focal adhesion motility revealed in stationary fibroblasts

7 July 2018

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Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

7 July 2018

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Interplay between Rac and Rho in the control of substrate contact dynamics

7 July 2018

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Src family kinases are required for integrin but not PDGFR signal transduction.

7 July 2018

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Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma

7 July 2018

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Three-dimensional structure of the tyrosine kinase c-Src

7 July 2018

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Regulation, substrates and functions of src

7 July 2018

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Reduced phosphotyrosine binding by the v-Src SH2 domain is compatible with wild-type transformation.

7 July 2018

1 reference

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Myristylation and palmitylation of Src family members: the fats of the matter

7 July 2018

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Highly conserved amino acids in the SH2 and catalytic domains of v-src are altered in naturally occurring, transformation-defective alleles.

7 July 2018

1 reference

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Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.

7 July 2018

1 reference

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Production of high-titer helper-free retroviruses by transient transfection

7 July 2018

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Ligand-dependent and -independent integrin focal contact localization: the role of the alpha chain cytoplasmic domain

7 July 2018

1 reference

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Protein modules and signalling networks

7 July 2018

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Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489135

Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489135

Linker insertion-deletion mutagenesis of the v-src gene: isolation of host- and temperature-dependent mutants

7 July 2018

1 reference

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A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489135

Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489135

Mutations in src homology regions 2 and 3 of activated chicken c-src that result in preferential transformation of mouse or chicken cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489135

Host range mutants of v-src: alterations in kinase activity and substrate interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489135

SH2 and SH3 domains: from structure to function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489135

Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489135

Intracellular targeting of pp60src expression: localization of v-src to adhesion plaques is sufficient to transform chicken embryo fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489135

Receptor protein tyrosine phosphatase alpha activates Src-family kinases and controls integrin-mediated responses in fibroblasts

7 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16738308

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.01147-05

1 reference

4 August 2017

1 reference

4 August 2017

1 reference