O-GlcNAc and the epigenetic regulation of gene expression (Q34683048)

3 August 2017

1 reference

title

O-GlcNAc and the epigenetic regulation of gene expression (English)

1 reference

3 August 2017

Brian A Lewis

1 reference

3 August 2017

John A Hanover

series ordinal

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3 August 2017

language of work or name

English

0 references

publication date

21 October 2014

1 reference

Journal of Biological Chemistry

3 August 2017

published in

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3 August 2017

volume

289

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3 August 2017

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3 August 2017

page(s)

34440-34448

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Targeted placental deletion of OGT recapitulates the prenatal stress phenotype including hypothalamic mitochondrial dysfunction

3 August 2017

cites work

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7 July 2018

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7 July 2018

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Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked β-N-acetylglucosamine transferase (OGT).

7 July 2018

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HCF-1 Is Cleaved in the Active Site of O-GlcNAc Transferase

7 July 2018

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The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases

7 July 2018

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Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells

7 July 2018

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The nexus of chromatin regulation and intermediary metabolism.

7 July 2018

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Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain

7 July 2018

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Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

7 July 2018

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RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and Template

7 July 2018

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The RNA polymerase II carboxy-terminal domain (CTD) code

7 July 2018

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The writers, readers, and functions of the RNA polymerase II C-terminal domain code

7 July 2018

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Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells

7 July 2018

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Cracking the O-GlcNAc code in metabolism.

7 July 2018

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O-GlcNAc cycling: a link between metabolism and chronic disease

7 July 2018

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Influence of metabolism on epigenetics and disease

7 July 2018

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Emerging roles for chromatin as a signal integration and storage platform

7 July 2018

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Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat

7 July 2018

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TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

7 July 2018

1 reference

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TET2 promotes histone O-GlcNAcylation during gene transcription

7 July 2018

1 reference

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Transcription-associated histone modifications and cryptic transcription

7 July 2018

1 reference

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Evidence of the involvement of O-GlcNAc-modified human RNA polymerase II CTD in transcription in vitro and in vivo

7 July 2018

1 reference

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O-GlcNAcylation of kinases

7 July 2018

1 reference

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Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation

7 July 2018

1 reference

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BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain

7 July 2018

1 reference

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A two-way street: reciprocal regulation of metabolism and signalling.

7 July 2018

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β-N-Acetylglucosamine (O-GlcNAc) is a novel regulator of mitosis-specific phosphorylations on histone H3

7 July 2018

1 reference

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Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis

7 July 2018

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Dynamic O-GlcNAc modification regulates CREB-mediated gene expression and memory formation

7 July 2018

1 reference

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RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing

7 July 2018

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AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

7 July 2018

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Modification of histones by sugar β-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

O-GlcNAc signalling: implications for cancer cell biology

7 July 2018

1 reference

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Phosphorylation of RNAPII: To P-TEFb or not to P-TEFb?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Polycomb repressive complex 2 is necessary for the normal site-specific O -GlcNAc distribution in mouse embryonic stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

The C-terminal domain of RNA polymerase II is modified by site-specific methylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Structure of human O-GlcNAc transferase and its complex with a peptide substrate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Epigenetics gets sweeter: O-GlcNAc joins the "histone code".

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Beta-N-acetylglucosamine (O-GlcNAc) is part of the histone code

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Blocking O-Linked GlcNAc Cycling in Drosophila Insulin-producing Cells Perturbs Glucose-Insulin Homeostasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

O-GlcNAc cycling: emerging roles in development and epigenetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

The integrator complex recognizes a new double mark on the RNA polymerase II carboxyl-terminal domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

O-GlcNAc cycling enzymes associate with the translational machinery and modify core ribosomal proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity

7 July 2018

1 reference

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Recruitment of polycomb complexes: a role for SCM.

7 July 2018

1 reference

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Modulation of transcription factor function by O-GlcNAc modification

7 July 2018

1 reference

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The foundation of extranuclear inheritance: plastid and mitochondrial genetics

7 July 2018

1 reference

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Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic beta cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

O-GlcNAc regulates FoxO activation in response to glucose

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

MGEA5-14 polymorphism and type 2 diabetes in Mexico City

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Trithorax-group protein ASH1 methylates histone H3 lysine 36.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Phosphorylation energy hypothesis: open chemical systems and their biological functions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Ataxin-10 interacts with O-linked beta-N-acetylglucosamine transferase in the brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

THE FEEDBACK CONTROL OF SUGAR NUCLEOTIDE BIOSYNTHESIS IN LIVER

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

ASH1, a Drosophila trithorax group protein, is required for methylation of lysine 4 residues on histone H3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Roles of the Tetratricopeptide Repeat Domain in O-GlcNAc Transferase Targeting and Protein Substrate Specificity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Nuclear c-Abl is a COOH-terminal repeated domain (CTD)-tyrosine (CTD)-tyrosine kinase-specific for the mammalian RNA polymerase II: possible role in transcription elongation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by the Abl-related gene product.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Identification of a binding site in c-Ab1 tyrosine kinase for the C-terminal repeated domain of RNA polymerase II.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Identification of a uridine nucleotide-selective G-protein-linked receptor that activates phospholipase C.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

A gene that regulates the bithorax complex differentially in larval and adult cells of Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Lymphocyte activation induces rapid changes in nuclear and cytoplasmic glycoproteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

The interaction of RNA polymerase II with the adenovirus-2 major late promoter is precluded by phosphorylation of the C-terminal domain of subunit IIa

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263851

Reciprocity between O-GlcNAc and O-phosphate on the carboxyl terminal domain of RNA polymerase II.

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.595439

A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.595439

Mitochondrial and nucleocytoplasmic isoforms of O-linked GlcNAc transferase encoded by a single mammalian gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.595439

Recombinant O-GlcNAc transferase isoforms: identification of O-GlcNAcase, yes tyrosine kinase, and tau as isoform-specific substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.595439

TET3-OGT interaction increases the stability and the presence of OGT in chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.595439

CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.595439

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.595439

Hepatic glucose sensing via the CREB coactivator CRTC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.595439

Essential role of the glycosyltransferase sxc/Ogt in polycomb repression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R114.595439

RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc

21 January 2018

1 reference

12 December 2020

UDP-GlcNAc transport across the Golgi membrane: electroneutral exchange for dianionic UMP

1 reference

12 December 2020

Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase

1 reference

12 December 2020

Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.R114.595439

1 reference

3 August 2017

1 reference

3 August 2017

1 reference