A RIP tide in neuronal signal transduction (Q34682414)

3 August 2017

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title

A RIP tide in neuronal signal transduction (English)

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3 August 2017

Julius O Ebinu

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3 August 2017

Bruce A Yankner

series ordinal

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3 August 2017

language of work or name

English

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publication date

1 May 2002

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3 August 2017

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

499-502

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

3 August 2017

cites work

1 reference

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7 January 2021

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

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7 January 2021

The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

1 reference

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7 January 2021

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

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Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch

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7 January 2021

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

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Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.

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7 January 2021

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

1 reference

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7 January 2021

Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.

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7 January 2021

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

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7 January 2021

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

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Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4

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7 January 2021

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

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7 January 2021

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

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7 January 2021

Translating cell biology into therapeutic advances in Alzheimer's disease

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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7 January 2021

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

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7 January 2021

Mechanisms of neuronal degeneration in Alzheimer's disease

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7 January 2021

Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains

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7 January 2021

Apoptosis in the nervous system

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7 January 2021

Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1

1 reference

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7 January 2021

10.1016/S0896-6273(02)00704-3

Identifiers

DOI

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3 August 2017

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