Mechanistic considerations in benzene physiological model development (Q34637602)

3 August 2017

2 references

19 September 2019

7 November 2019

Mechanistic considerations in benzene physiological model development (English)

1 reference

biomedical investigative technique

3 August 2017

main subject

1 reference

19 September 2019

1 reference

7 November 2019

1 reference

M A Medinsky

1 reference

3 August 2017

E M Kenyon

series ordinal

1 reference

3 August 2017

M J Seaton

series ordinal

1 reference

3 August 2017

P M Schlosser

series ordinal

1 reference

3 August 2017

publication date

1 December 1996

3 references

Environmental Health Perspectives

3 August 2017

19 September 2019

7 November 2019

3 references

3 August 2017

19 September 2019

7 November 2019

104 Suppl 6

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3 August 2017

page(s)

1399-1404

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Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo.

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Benzene and phenol metabolism by mouse and rat liver microsomes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

A perspective on benzene leukemogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

In vitro conjugation of benzene metabolites by human liver: potential influence of interindividual variability on benzene toxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling to understanding the mechanism of action of hazardous substances

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Retrograde perfusion to probe the heterogeneous distribution of hepatic drug metabolizing enzymes in rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Modifications in the myeloclastogenic effect of benzene in mice with toluene, phenobarbital, 3-methylcholanthrene, Aroclor 1254 and SKF-525A.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Induction of micronuclei by benzene in B6C3F1 mice: retrospective analysis of peripheral blood smears from the NTP carcinogenesis bioassay.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Benzene and leukemia. An epidemiologic risk assessment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

An interaction of benzene metabolites reproduces the myelotoxicity observed with benzene exposure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

A physiological model for simulation of benzene metabolism by rats and mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Genotoxicity of two metabolites of benzene: phenol and hydroquinone show strong synergistic effects in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Synergistic action of the benzene metabolite hydroquinone on myelopoietic stimulating activity of granulocyte/macrophage colony-stimulating factor in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Metabolic zonation of the liver: regulation and implications for liver function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Benzene toxicity: a critical evaluation: hematotoxicity in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Measurement of adducts of benzoquinone with hemoglobin and albumin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Production of benzoquinone adducts with hemoglobin and bone-marrow proteins following administration of [13C6]benzene to rats.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Benzene metabolism by human liver microsomes in relation to cytochrome P450 2E1 activity.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Sister chromatid exchange induction in human lymphocytes exposed to benzene and its metabolites in vitro.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1469768

Comparison of protein adducts of benzene oxide and benzoquinone in the blood and bone marrow of rats and mice exposed to [14C/13C6]benzene

26 October 2018

1 reference

12 December 2020

The effect of exposure regimen and duration on benzene-induced bone-marrow damage in mice. I. Sex comparison in DBA/2 mice

1 reference

12 December 2020

Dose-, route-, and sex-dependent urinary excretion of phenol metabolites in B6C3F1 mice

1 reference

12 December 2020

Benzene and the genotoxicity of its metabolites. II. The effect of the route of administration on the micronuclei and bone marrow depression in mouse bone marrow cells

1 reference

12 December 2020

Identification of ethanol-inducible P450 isozyme 3a (P450IIE1) as a benzene and phenol hydroxylase

1 reference

12 December 2020

Effect of exposure concentration, exposure rate, and route of administration on metabolism of benzene by F344 rats and B6C3F1 mice

1 reference

12 December 2020

Kinetics of metabolite formation and elimination in the perfused rat liver preparation: differences between the elimination of preformed acetaminophen and acetaminophen formed from phenacetin

1 reference

12 December 2020

Benzene disposition in the rat after exposure by inhalation

1 reference

12 December 2020

Benzene exposure in the United States 1978-1983: an overview

1 reference

12 December 2020

Effect of dose on the absorption and excretion of [14C]benzene administered orally or by inhalation in rats and mice

1 reference

12 December 2020

Competition between two enzymes for substrate removal in liver: modulating effects due to substrate recruitment of hepatocyte activity

1 reference

12 December 2020

Benzene and the genotoxicity of its metabolites. I. Transplacental activity in mouse fetuses and in their dams

1 reference

12 December 2020

Benzene and benzene metabolites as embryotoxic agents: effects on cultured rat embryos

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.961041399

1 reference

release_2uhfpv6ri5bapmpnpogaxgdhz4

3 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2uhfpv6ri5bapmpnpogaxgdhz4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1469768

1 reference

3 August 2017

1 reference