Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain (Q34601695)

25389312

3 August 2017

title

Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain (English)

1 reference

3 August 2017

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8 June 2020

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8 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25389312%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25389312%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25389312%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Charlotte Simonsen

1 reference

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8 June 2020

Per Kjellbom

series ordinal

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8 June 2020

Edward D Högestätt

series ordinal

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8 June 2020

language of work or name

English

0 references

publication date

11 November 2014

1 reference

25389312

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

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volume

111

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issue

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8 June 2020

page(s)

16901-16906

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H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway

8 June 2020

cites work

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Directionality of temperature activation in mouse TRPA1 ion channel can be inverted by single-point mutations in ankyrin repeat six.

7 July 2018

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Species differences and molecular determinant of TRPA1 cold sensitivity

7 July 2018

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Benzoquinone reveals a cysteine-dependent desensitization mechanism of TRPA1.

7 July 2018

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TRPV1 channels are intrinsically heat sensitive and negatively regulated by phosphoinositide lipids

7 July 2018

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A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel

7 July 2018

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Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception

7 July 2018

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Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies

7 July 2018

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Differential expression and functionality of TRPA1 protein genetic variants in conditions of thermal stimulation.

7 July 2018

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Species comparison and pharmacological characterization of human, monkey, rat, and mouse TRPA1 channels

7 July 2018

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Quantifying and modeling the temperature-dependent gating of TRP channels

7 July 2018

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Identification of in vivo disulfide conformation of TRPA1 ion channel

7 July 2018

1 reference

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Modulation of TRPA1 thermal sensitivity enables sensory discrimination in Drosophila

7 July 2018

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A thermodynamic framework for understanding temperature sensing by transient receptor potential (TRP) channels

7 July 2018

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TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcol

7 July 2018

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Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli.

7 July 2018

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Molecular architecture and subunit organization of TRPA1 ion channel revealed by electron microscopy

7 July 2018

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Irritating channels: the case of TRPA1

7 July 2018

1 reference

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Gating of transient receptor potential melastatin 8 (TRPM8) channels activated by cold and chemical agonists in planar lipid bilayers

7 July 2018

1 reference

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Infrared snake eyes: TRPA1 and the thermal sensitivity of the snake pit organ.

7 July 2018

1 reference

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A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome

7 July 2018

1 reference

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Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception.

7 July 2018

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Molecular basis of infrared detection by snakes

7 July 2018

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TRPA1 acts as a cold sensor in vitro and in vivo

7 July 2018

1 reference

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Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels

7 July 2018

1 reference

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TRPA1 mediates the noxious effects of natural sesquiterpene deterrents

7 July 2018

1 reference

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Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphate

7 July 2018

1 reference

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Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

7 July 2018

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Cold sensitivity of recombinant TRPA1 channels

7 July 2018

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Direct activation of the ion channel TRPA1 by Ca2+.

7 July 2018

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Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

7 July 2018

1 reference

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TRP channel activation by reversible covalent modification

7 July 2018

1 reference

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A hot-sensing cold receptor: C-terminal domain determines thermosensation in transient receptor potential channels.

7 July 2018

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Sensing with TRP channels

7 July 2018

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Structural mechanism of plant aquaporin gating

7 July 2018

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Pungent products from garlic activate the sensory ion channel TRPA1

7 July 2018

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The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin.

7 July 2018

1 reference

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Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin

7 July 2018

1 reference

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Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250169

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4250169

Residues in the pore region of Drosophila transient receptor potential A1 dictate sensitivity to thermal stimuli

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1412689111

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25389312

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12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1412689111

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8 June 2020

0 references

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8 June 2020

25389312

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