L-Dihydroxyphenylserine (L-DOPS): a norepinephrine prodrug (Q34600042)

3 August 2017

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title

L-Dihydroxyphenylserine (L-DOPS): a norepinephrine prodrug (English)

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3 August 2017

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David S Goldstein

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3 August 2017

publication date

1 September 2006

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Cardiovascular Drug Reviews

3 August 2017

published in

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3 August 2017

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3 August 2017

issue

3-4

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3 August 2017

page(s)

189-203

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Endogenous restoration of noradrenaline by precursor therapy in dopamine-beta-hydroxylase deficiency

3 August 2017

cites work

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The formation of noradrenaline from dihydroxyphenylserine

21 January 2018

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Improved orthostatic tolerance in familial amyloidotic polyneuropathy with unnatural noradrenaline precursor L-threo-3,4-dihydroxyphenylserine.

21 January 2018

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Dysautonomia in Parkinson's disease: neurocardiological abnormalities

21 January 2018

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Orthostatic hypotension from sympathetic denervation in Parkinson's disease

21 January 2018

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Pandysautonomia associated with impaired ganglionic neurotransmission and circulating antibody to the neuronal nicotinic receptor

21 January 2018

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Cardiac sympathetic dysautonomia in chronic orthostatic intolerance syndromes

21 January 2018

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Clinical pharmacokinetics of the norepinephrine precursor L-threo-DOPS in primary chronic autonomic failure

21 January 2018

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Autoimmune autonomic failure in a patient with myeloma-associated Shy-Drager syndrome

21 January 2018

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Orthostatic hypotension in Parkinson's disease

21 January 2018

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Preliminary observations on the use of midodrine hydrochloride in the treatment of refractory neurocardiogenic syncope

21 January 2018

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Neuropathology of immunohistochemically identified brainstem neurons in Parkinson's disease

21 January 2018

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The pharmacokinetics of intravenous and oral levodopa in patients with Parkinson's disease who exhibit on-off fluctuations

21 January 2018

1 reference

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Effect of L-threo-3,4-dihydroxyphenylserine on muscle sympathetic nerve activity in humans

21 January 2018

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The neuropathic postural tachycardia syndrome

21 January 2018

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Neurogenic orthostatic hypotension: A double-blind, placebo-controlled study with midodrine

21 January 2018

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Assessment of human sympathetic nervous system activity from measurements of norepinephrine turnover

21 January 2018

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Effect of L-threo-3,4-dihydroxyphenylserine on muscle sympathetic nerve activities in Shy-Drager syndrome

21 January 2018

1 reference

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Plasma and cerebrospinal fluid neurochemical pattern in Menkes disease

21 January 2018

1 reference

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Studies on the activity of L-threo-3,4-dihydroxyphenylserine (L-DOPS) as a catecholamine precursor in the brain. Comparison with that of L-dopa

21 January 2018

1 reference

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Reversal of the reserpine-induced ptosis by L-threo-3,4-dihydroxy-phenylserine (L-threo-DOPS), a (-)-norepinephrine precursor, and its potentiation by imipramine or nialamide

21 January 2018

1 reference

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Differential effect of L-threo-3,4-dihydroxyphenylserine in pure autonomic failure and multiple system atrophy with autonomic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Norepinephrine precursor therapy in neurogenic orthostatic hypotension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

The noradrenaline precursor L-threo-3,4-dihydroxyphenylserine exhibits antinociceptive activity via central alpha-adrenoceptors in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

A new metabolic pathway of L-threo-3,4-dihydroxyphenylserine, a precursor amino acid of norepinephrine, in the brain. Studies by in vivo microdialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

L-threo-dihydroxyphenylserine (L-threo-DOPS; droxidopa) in the management of neurogenic orthostatic hypotension: a multi-national, multi-center, dose-ranging study in multiple system atrophy and pure autonomic failure

21 January 2018

1 reference

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Effect of L-threo-3, 4-dihydroxyphenylserine on orthostatic hypotension in a patient with spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Incorporation of glycosylated beta-galactosidase into bovine brain synaptosomes

21 January 2018

1 reference

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L-threo-3,4-dihydroxyphenylserine (DOPS) aldolase: a new enzyme cleaving DOPS into protocatechualdehyde and glycine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

The norepinephrine precursor L-threo-3,4-dihydroxyphenylserine facilitates motor recovery in chronic stroke patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Usefulness of midodrine in patients with severely symptomatic neurocardiogenic syncope: a randomized control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Effects of L-threo-DOPS, an L-noradrenaline precursor, on locus coeruleus-originating neurons in spinal trigeminal nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Farewell to the "Shy-Drager syndrome".

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

The effects of L-threo-dihydroxyphenylserine on norepinephrine metabolism in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

A neurological syndrome associated with orthostatic hypotension: a clinical-pathologic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Orthostatic hypotension in familial amyloid polyneuropathy: treatment with DL-threo-3,4-dihydroxyphenylserine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Treatment of parkinsonism with L-threo-3,4-dihydroxyphenylserine: a pharmacokinetic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

The effects of the noradrenaline precursor, L-threo-3,4-dihydroxyphenylserine, in children with orthostatic intolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Congenital dopamine-beta-hydroxylase deficiency in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Blood-brain barrier for adrenaline

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

The uptake of circulating [3H]norepinephrine by the pituitary gland and various areas of the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

L-threo-3,4-dihydroxyphenylserine treatment for gait apraxia in parkinsonian patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

Pure akinesia manifested neuroleptic malignant syndrome: a clinical variant of progressive supranuclear palsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3466.2006.00189.X

10.1111/J.1527-3466.2006.00189.X

21 January 2018

Identifiers

DOI

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3 August 2017

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