Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol (Q34597859)

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English	Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

Zenaide Quezado

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Zenaide Quezado

6

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author name string

Hui Wei

1

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Europe PubMed Central

PubMed publication ID

3 August 2017

Zhongjian Zhang

2

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Europe PubMed Central

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3 August 2017

Arjun Saha

3

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Europe PubMed Central

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3 August 2017

Shiyong Peng

4

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Europe PubMed Central

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3 August 2017

Goutam Chandra

5

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Europe PubMed Central

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3 August 2017

Anil B Mukherjee

7

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PubMed publication ID

3 August 2017

publication date

28 December 2010

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Europe PubMed Central

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3 August 2017

Human Molecular Genetics

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Europe PubMed Central

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3 August 2017

20

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Europe PubMed Central

PubMed publication ID

3 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1111-1121

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

Caloric restriction, SIRT1 and longevity

1 reference

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7 July 2018

Recent progress in the biology and physiology of sirtuins

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7 July 2018

Children with infantile neuronal ceroid lipofuscinosis have an increased risk of hypothermia and bradycardia during anesthesia

1 reference

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7 July 2018

Transcriptional control of mitochondrial biogenesis and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

The TOR pathway comes of age

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7 July 2018

Resveratrol and neurodegenerative diseases: activation of SIRT1 as the potential pathway towards neuroprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

1 reference

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7 July 2018

RAGE signaling contributes to neuroinflammation in infantile neuronal ceroid lipofuscinosis

1 reference

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7 July 2018

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

1 reference

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7 July 2018

Mitochondrial fragmentation in neurodegeneration

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7 July 2018

FoxO transcription factors in oxidative stress response and ageing--a new fork on the way to longevity?

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7 July 2018

Transcriptional control of mitochondrial energy metabolism through the PGC1 coactivators.

1 reference

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7 July 2018

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

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7 July 2018

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

1 reference

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7 July 2018

Sirtuins in mammals: insights into their biological function

1 reference

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7 July 2018

Production of lysophosphatidylcholine by cPLA2 in the brain of mice lacking PPT1 is a signal for phagocyte infiltration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

Resveratrol improves health and survival of mice on a high-calorie diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

From genes to systems: new global strategies for the characterization of NCL biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

Progress towards understanding disease mechanisms in small vertebrate models of neuronal ceroid lipofuscinosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

The neuronal ceroid-lipofuscinoses: from past to present

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

Molecular genetics of the NCLs -- status and perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3043662

7 July 2018

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

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7 July 2018

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

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7 July 2018

Blood to brain to the rescue.

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7 July 2018

Current state of clinical and morphological features in human NCL.

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7 July 2018

The AMP-activated protein kinase cascade--a unifying system for energy control

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7 July 2018

Neuronal degeneration and mitochondrial dysfunction

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7 July 2018

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

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7 July 2018

Activation of AMPK is essential for AICAR-induced glucose uptake by skeletal muscle but not adipocytes

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7 July 2018

Brain-directed gene therapy for lysosomal storage disease: going well beyond the blood- brain barrier

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Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

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Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis

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7 July 2018

ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones

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Regional and cellular neuropathology in the palmitoyl protein thioesterase-1 null mutant mouse model of infantile neuronal ceroid lipofuscinosis

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SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons

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Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

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Lysosomal dysfunction results in altered energy balance

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Increased wheel-running activity in the genetically skeletal muscle fast-twitch fiber-dominant rats

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12 December 2020

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10.1093/HMG/DDQ555

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

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3 August 2017

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