Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells (Q34574858)

3 August 2017

title

Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells (English)

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3 August 2017

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Julie C Fitzgerald

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Federico Mingozzi

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3 August 2017

Eric Dobrzynski

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3 August 2017

Ou Cao

series ordinal

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3 August 2017

Lixin Wang

series ordinal

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3 August 2017

Roland W Herzog

series ordinal

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3 August 2017

language of work or name

English

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publication date

10 March 2006

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Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

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3 August 2017

volume

103

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3 August 2017

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3 August 2017

page(s)

4592-4597

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Systemic protein delivery by muscle-gene transfer is limited by a local immune response

3 August 2017

cites work

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7 July 2018

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Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer

7 July 2018

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7 July 2018

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Control of regulatory T cell development by the transcription factor Foxp3

7 July 2018

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AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.

7 July 2018

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Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors

7 July 2018

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Fas-mediated apoptosis causes elimination of virus-specific cytotoxic T cells in the virus-infected liver

7 July 2018

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Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway.

7 July 2018

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Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibers

7 July 2018

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7 July 2018

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7 July 2018

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Successful expression of human factor IX following repeat administration of adenoviral vector in mice.

7 July 2018

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Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo

7 July 2018

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MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses.

7 July 2018

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Novel hemophilia B mouse models exhibiting a range of mutations in the Factor IX gene.

7 July 2018

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Role of vector in activation of T cell subsets in immune responses against the secreted transgene product factor IX.

21 January 2018

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Major role of local immune responses in antibody formation to factor IX in AAV gene transfer

21 January 2018

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Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice

21 January 2018

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Evasion of immune responses to introduced human acid alpha-glucosidase by liver-restricted expression in glycogen storage disease type II.

21 January 2018

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Sustained phenotypic correction of hemophilia B dogs with a factor IX null mutation by liver-directed gene therapy

21 January 2018

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Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA.

21 January 2018

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Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors

21 January 2018

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Induction of antigen-specific CD4+ T-cell anergy and deletion by in vivo viral gene transfer

21 January 2018

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AAV2 vector harboring a liver-restricted promoter facilitates sustained expression of therapeutic levels of alpha-galactosidase A and the induction of immune tolerance in Fabry mice.

21 January 2018

1 reference

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Neonatal gene transfer with a retroviral vector results in tolerance to human factor IX in mice and dogs

21 January 2018

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Adeno-associated viral vector-mediated gene transfer of human blood coagulation factor IX into mouse liver

21 January 2018

1 reference

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Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16537361

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Humoral immune response in mice against a circulating antigen induced by adenoviral transfer is strictly dependent on expression in antigen-presenting cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16537361

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0508685103

1 reference

3 August 2017

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3 August 2017

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