A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear (Q34550656)

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1 April 2020

title

A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear (English)

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1 April 2020

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1 April 2020

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1 April 2020

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1 April 2020

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1 April 2020

Sarah J Wassmer

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1 April 2020

Sarah D Gluck

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1 April 2020

Alice Galvin

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1 April 2020

Ruth Taylor

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1 April 2020

Andrew Forge

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1 April 2020

Konstantina M Stankovic

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1 April 2020

Jeffrey R Holt

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1 April 2020

publication date

6 February 2017

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1 April 2020

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volume

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issue

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1 April 2020

page(s)

280-284

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A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records

1 April 2020

cites work

1 reference

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Outcomes review of modern hearing preservation technique in cochlear implant

7 July 2018

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Secreted Factors from Human Vestibular Schwannomas Can Cause Cochlear Damage.

7 July 2018

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Gene Therapy Restores Hair Cell Stereocilia Morphology in Inner Ears of Deaf Whirler Mice.

7 July 2018

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In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector

7 July 2018

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Tmc gene therapy restores auditory function in deaf mice

7 July 2018

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The application of genome editing in studying hearing loss

7 July 2018

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Cochlear gene transfer mediated by adeno-associated virus: Comparison of two surgical approaches

7 July 2018

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Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse

7 July 2018

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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

7 July 2018

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Genetic investigations in childhood deafness

7 July 2018

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Gene therapy for sensorineural hearing loss

7 July 2018

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Sound strategies for hearing restoration.

7 July 2018

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Lgr5-positive supporting cells generate new hair cells in the postnatal cochlea

7 July 2018

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Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial.

7 July 2018

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7 July 2018

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Inner ear supporting cells protect hair cells by secreting HSP70.

7 July 2018

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Lessons learned from the clinical development and market authorization of Glybera.

7 July 2018

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A brief history of hair cell regeneration research and speculations on the future

7 July 2018

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Gene therapy for the inner ear

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5340646

Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapy.

7 July 2018

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Progress in cochlear physiology after Békésy

7 July 2018

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Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

7 July 2018

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Auditory mechanics of the tectorial membrane and the cochlear spiral

7 July 2018

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Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear.

7 July 2018

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The challenge of hair cell regeneration

7 July 2018

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Adenoviral and AAV-mediated gene transfer to the inner ear: role of serotype, promoter, and viral load on in vivo and in vitro infection efficiencies.

7 July 2018

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A technique for serial collection of cerebrospinal fluid from the cisterna magna in mouse

7 July 2018

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Safety and efficacy of gene transfer for Leber's congenital amaurosis

7 July 2018

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An in vitro model system to study gene therapy in the human inner ear.

7 July 2018

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Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells

7 July 2018

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7 July 2018

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Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals

7 July 2018

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A comprehensive network and pathway analysis of human deafness genes

7 July 2018

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Specific and efficient transduction of Cochlear inner hair cells with recombinant adeno-associated virus type 3 vector

21 January 2018

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HCN channels expressed in the inner ear are necessary for normal balance function

21 January 2018

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Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice

21 January 2018

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Unilateral hemispherectomy at adulthood asymmetrically affects motor performance of male Swiss mice.

21 January 2018

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Structural evidence for ion transport and tectorial membrane maintenance in the gerbil limbus

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NBT.3781

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1 April 2020

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1 April 2020

PubMed publication ID

28165475

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