Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease (Q34556739)

3 August 2017

title

Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease (English)

1 reference

3 August 2017

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Carmela R Abraham

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Clinton T Baldwin

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Kathryn L Lunetta

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Lindsay A Farrer

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Robert C Green

1 reference

3 August 2017

L Adrienne Cupples

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3 August 2017

Porat M Erlich

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3 August 2017

publication date

27 October 2010

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3 August 2017

published in

Neurobiology of Aging

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

1015.e7-23

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A common mutation in paraoxonase-2 results in impaired lactonase activity.

3 August 2017

cites work

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7 July 2018

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Responsiveness to cholinesterase inhibitors in Alzheimer's disease: a possible role for the 192 Q/R polymorphism of the PON-1 gene.

7 July 2018

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Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase

7 July 2018

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Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities

7 July 2018

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Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes

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Possible association between Cys311Ser polymorphism of paraoxonase 2 gene and late-onset Alzheimer's disease in Chinese

7 July 2018

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Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3.

7 July 2018

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Paraoxonase-1 promoter haplotypes and serum paraoxonase: a predominant role for polymorphic position - 107, implicating the Sp1 transcription factor

7 July 2018

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Codon 311 (Cys --> Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias

7 July 2018

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Risk of dementia among white and African American relatives of patients with Alzheimer disease.

7 July 2018

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Effects of 5' regulatory-region polymorphisms on paraoxonase-gene (PON1) expression

7 July 2018

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Polymorphisms in the human paraoxonase (PON1) promoter

7 July 2018

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No association of paraoxonase gene polymorphism with atherosclerosis or Alzheimer's disease

7 July 2018

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Molecular basis for the polymorphic forms of human serum paraoxonase/arylesterase: glutamine or arginine at position 191, for the respective A or B allozymes.

7 July 2018

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New chromogenic and fluorogenic substrates for the determination of butyrylcholinesterase and arylesterase activities

7 July 2018

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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

7 July 2018

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Distribution of paraoxon hydrolytic activity in the serum of patients after myocardial infarction.

7 July 2018

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Involvement of paraoxonase 1 genetic variants in Alzheimer's disease neuropathology

7 July 2018

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Paraoxonase activity and dementia

27 October 2018

1 reference

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Association between PON1 5'-regulatory region polymorphisms, PON1 activity and ischemic stroke

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Polymorphisms at the paraoxonase 1 L55M and Q192R loci affect the pathophysiology of Alzheimer's disease: emphasis on the cholinergic system and beta-amyloid levels.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Association study of the paraoxonase 1 gene with the risk of developing Alzheimer's disease.

27 October 2018

1 reference

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Association of paraoxonase activity and coronary blood flow.

27 October 2018

1 reference

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Association analysis of the paraoxonase-1 gene with Alzheimer's disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Gln192Arg polymorphism in paraoxonase 1 gene is associated with Alzheimer disease in a Chinese Han ethnic population.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Polymorphisms in the PON gene cluster are associated with Alzheimer disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Haplotype-phenotype relationships of paraoxonase-1.

27 October 2018

1 reference

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Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies

27 October 2018

1 reference

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Low paraoxonase activity predicts coronary events in the Caerphilly Prospective Study

27 October 2018

1 reference

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Different pattern of association of paraoxonase Gln192-->Arg polymorphism with sporadic late-onset Alzheimer's disease and coronary artery disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Lack of association between Alzheimer's disease and Gln-Arg 192 Q/R polymorphism of the PON-1 gene in an Italian population.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Paraoxonase 1 192/55 gene polymorphisms in Alzheimer's disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Paraoxonase 1 activity: a new vascular marker of dementia?

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Paraoxonase promoter polymorphism T(-107)C and relative paraoxonase deficiency as determinants of risk of coronary artery disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Paraoxonase (PON1) phenotype is a better predictor of vascular disease than is PON1(192) or PON1(55) genotype.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Determination of paraoxonase (PON1) status requires more than genotyping.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Studies on human serum paraoxonase/arylesterase

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Spectrophotometric assays for the enzymatic hydrolysis of the active metabolites of chlorpyrifos and parathion by plasma paraoxonase/arylesterase.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Validation of a Telephone Version of the Mini-Mental State Examination

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3034817

Serum paraoxonase activity in familial hypercholesterolaemia and insulin-dependent diabetes mellitus

27 October 2018

1 reference

12 December 2020

Serum paraoxonase (PON1) 55 and 192 polymorphism and paraoxonase activity and concentration in non-insulin dependent diabetes mellitus

1 reference

12 December 2020

Chromogenic and fluorogenic assays for the lactonase activity of serum paraoxonases

1 reference

12 December 2020

PON1 55/192 polymorphism, oxidative stress, type, prognosis and severity of stroke

1 reference

12 December 2020

The 192R/Q polymorphs of serum paraoxonase PON1 differ in HDL binding, lipolactonase stimulation, and cholesterol efflux

1 reference

12 December 2020

Accuracy and biological variation of human serum paraoxonase 1 activity and polymorphism (Q192R) by kinetic enzyme assay

1 reference

12 December 2020

Interactions and associations of paraoxonase gene cluster polymorphisms with myocardial infarction in a Pakistani population

1 reference

12 December 2020

Hydrolysis of diacetylmorphine (heroin) by human serum cholinesterase

1 reference

12 December 2020

Characteristics of the genetically determined allozymic forms of human serum paraoxonase/arylesterase

1 reference

12 December 2020

10.1016/J.NEUROBIOLAGING.2010.08.003

Identifiers

DOI

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3 August 2017

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3 August 2017

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