Hyperforin, a new lead compound against the progression of cancer and leukemia? (Q34540807)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16791262%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

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title

Hyperforin, a new lead compound against the progression of cancer and leukemia? (English)

1 reference

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25 December 2019

1 reference

1 reference

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25 December 2019

C Billard

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25 December 2019

C Salanoubat

series ordinal

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25 December 2019

J D Fourneron

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25 December 2019

J P Kolb

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25 December 2019

publication date

22 June 2006

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25 December 2019

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25 December 2019

volume

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25 December 2019

issue

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25 December 2019

page(s)

1519-1525

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Pro-apoptotic properties of hyperforin in leukemic cells from patients with B-cell chronic lymphocytic leukemia

25 December 2019

cites work

1 reference

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Hyperforin inhibits MMP-9 secretion by B-CLL cells and microtubule formation by endothelial cells

21 January 2018

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St John's wort: Prozac from the plant kingdom.

21 January 2018

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The antidepressant mechanism of Hypericum perforatum.

21 January 2018

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The structure of hyperforin

21 January 2018

1 reference

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Biosynthesis of hyperforin in Hypericum perforatum

21 January 2018

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St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties.

21 January 2018

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Quantitative analysis of the major constituents of St John's wort with HPLC-ESI-MS.

21 January 2018

1 reference

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Hypericin in cancer treatment: more light on the way.

21 January 2018

1 reference

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Anti-inflammatory actions of St. John's wort: inhibition of human inducible nitric-oxide synthase expression by down-regulating signal transducer and activator of transcription-1alpha (STAT-1alpha) activation

21 January 2018

1 reference

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Role of hyperforin in the antidepressant-like activity of Hypericum perforatum extracts

21 January 2018

1 reference

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Hyperforin: more than an antidepressant bioactive compound?

21 January 2018

1 reference

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Is St John's wort a 'Prozac-like' herbal antidepressant?

21 January 2018

1 reference

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Hypericum perforatum (St John's Wort): a non-selective reuptake inhibitor? A review of the recent advances in its pharmacology

21 January 2018

1 reference

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Comparison of the synaptosomal uptake inhibition of serotonin by St John's wort products

21 January 2018

1 reference

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In vitro receptor screening of pure constituents of St. John's wort reveals novel interactions with a number of GPCRs

21 January 2018

1 reference

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Hyperforin represents the neurotransmitter reuptake inhibiting constituent of hypericum extract

21 January 2018

1 reference

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Stimulation of glutamate, aspartate and gamma-aminobutyric acid release from synaptosomes by hyperforin

21 January 2018

1 reference

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Synthesis and biological evaluation of hyperforin analogues. Part I. Modification of the enolized cyclohexanedione moiety

21 January 2018

1 reference

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Inhibition of synaptosomal uptake of 3H-L-glutamate and 3H-GABA by hyperforin, a major constituent of St. John's Wort: the role of amiloride sensitive sodium conductive pathways

21 January 2018

1 reference

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Inhibition of vesicular uptake of monoamines by hyperforin

21 January 2018

1 reference

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Hyperforin depletes synaptic vesicles content and induces compartmental redistribution of nerve ending monoamines

21 January 2018

1 reference

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The involvement of sodium and calcium ions in the release of amino acid neurotransmitters from mouse cortical slices elicited by hyperforin

21 January 2018

1 reference

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Hyperforin activates nonselective cation channels (NSCCs).

21 January 2018

1 reference

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Hyperforin modifies neuronal membrane properties in vivo

21 January 2018

1 reference

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Hyperforin stimulates intracellular calcium mobilisation and enhances extracellular acidification in DDT1-MF2 smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

Hypericum extract and hyperforin: memory-enhancing properties in rodents

21 January 2018

1 reference

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Stimulation of hippocampal acetylcholine release by hyperforin, a constituent of St. John's Wort

21 January 2018

1 reference

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Enhancement of proteolytic processing of the β-amyloid precursor protein by hyperforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

Topical application of St John's wort (Hypericum perforatum L.) and of its metabolite hyperforin inhibits the allostimulatory capacity of epidermal cells

21 January 2018

1 reference

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Studies on the antioxidative activity of phloroglucinol derivatives isolated from hypericum species

21 January 2018

1 reference

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Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase

21 January 2018

1 reference

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Suppression of receptor-mediated Ca2+ mobilization and functional leukocyte responses by hyperforin

21 January 2018

1 reference

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Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway.

21 January 2018

1 reference

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Antibacterial activity of hyperforin from St John's wort, against multiresistant Staphylococcus aureus and gram-positive bacteria.

21 January 2018

1 reference

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A current review of the antimicrobial activity of Hypericum perforatum L.

21 January 2018

1 reference

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Extracts from St John's Wort and their antimicrobial activity.

21 January 2018

1 reference

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Drug interactions with St John's wort : mechanisms and clinical implications

21 January 2018

1 reference

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Hyperforin content determines the magnitude of the St John's wort-cyclosporine drug interaction.

21 January 2018

1 reference

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Effect of the St. John's wort constituent hyperforin on docetaxel metabolism by human hepatocyte cultures

21 January 2018

1 reference

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Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures

21 January 2018

1 reference

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St John's wort, a herbal antidepressant, activates the steroid X receptor.

21 January 2018

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St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

21 January 2018

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Induction of Human CYP2C9 by Rifampicin, Hyperforin, and Phenobarbital Is Mediated by the Pregnane X Receptor

21 January 2018

1 reference

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Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia

21 January 2018

1 reference

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In vitro effects of the dicyclohexylammonium salt of hyperforin on interleukin-6 release in different experimental models

21 January 2018

1 reference

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Herbal modulation of P-glycoprotein

21 January 2018

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Quantitative characterization of direct P-glycoprotein inhibition by St John's wort constituents hypericin and hyperforin

21 January 2018

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Modulation of P-glycoprotein function by St John's wort extract and its major constituents

21 January 2018

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In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity

21 January 2018

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Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line.

21 January 2018

1 reference

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Comparison of the growth-inhibitory effect of Hypericum perforatum L. extracts, differing in the concentration of phloroglucinols and flavonoids, on leukaemia cells

21 January 2018

1 reference

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Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

Hyperforin inhibits cancer invasion and metastasis

21 January 2018

1 reference

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Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

The lipophilic extract of Hypericum perforatum exerts significant cytotoxic activity against T24 and NBT-II urinary bladder tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

Hyperforin, a bio-active compound of St. John's Wort, is a new inhibitor of angiogenesis targeting several key steps of the process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

Hyperforin acts as an angiogenesis inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers

21 January 2018

1 reference

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In vitro metabolism of hyperforin in rat liver microsomal systems

21 January 2018

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Current St John's wort research from mode of action to clinical efficacy

21 January 2018

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Pharmacological activity of hyperforin acetate in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

Aristoforin, a novel stable derivative of hyperforin, is a potent anticancer agent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

St. John's wort and its constituent hyperforin concordantly regulate expression of genes encoding enzymes involved in basic cellular pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404301

Analysis and stability of Hyperici oleum

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.LEU.2404301

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16791262%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 December 2019

1030706723

0 references

1 reference

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