Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice (Q34443174)

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English	Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice	scientific article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Dmitry V Kuprash

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Klaus Pfeffer

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Klaus Rajewsky

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Alexei V Tumanov

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Alexei V Tumanov

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Marat B Alimzhanov

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2 August 2017

Sergei I Grivennikov

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2 August 2017

Alexander N Shakhov

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2 August 2017

Ludmila N Drutskaya

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2 August 2017

Michael W Marino

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2 August 2017

Regina L Turetskaya

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2 August 2017

Arthur O Anderson

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2 August 2017

Sergei A Nedospasov

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publication date

1 December 2002

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2 August 2017

Molecular and Cellular Biology

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2 August 2017

22

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2 August 2017

24

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2 August 2017

8626-8634

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Europe PubMed Central

PubMed publication ID

2 August 2017

Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis

1 reference

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Expression profiling in knockout mice: lymphotoxin versus tumor necrosis factor in the maintenance of splenic microarchitecture

1 reference

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Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

1 reference

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The TNF and TNF receptor superfamilies: integrating mammalian biology

1 reference

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Secreted lymphotoxin-alpha is essential for the control of an intracellular bacterial infection.

1 reference

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SPLASH (PLA2IID), a novel member of phospholipase A2 family, is associated with lymphotoxin deficiency

1 reference

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The role of scavenger receptors in the innate immune system

1 reference

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Chemokines and cell migration in secondary lymphoid organs

1 reference

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The requirement of membrane lymphotoxin for the presence of dendritic cells in lymphoid tissues

1 reference

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6 July 2018

Lymphotoxin-beta-deficient mice show defective antiviral immunity.

1 reference

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6 July 2018

Cloning and recombinant expression of a novel mouse-secreted phospholipase A2.

1 reference

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6 July 2018

Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen

1 reference

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Susceptibility to Salmonella typhimurium infection and effectiveness of vaccination in mice deficient in the tumor necrosis factor alpha p55 receptor

1 reference

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6 July 2018

Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue

1 reference

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Listeriosis in p47(phox-/-) and TRp55-/- mice: protection despite absence of ROI and susceptibility despite presence of RNI

1 reference

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6 July 2018

Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Characterization of tumor necrosis factor-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

On the key role of secondary lymphoid organs in antiviral immune responses studied in alymphoplastic (aly/aly) and spleenless (Hox11(-)/-) mutant mice.

1 reference

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6 July 2018

Lymphotoxin-alpha (LTalpha) supports development of splenic follicular structure that is required for IgG responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Inter-relationship among macrophages, natural killer cells and neutrophils in early stages of Listeria resistance

1 reference

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6 July 2018

Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re

1 reference

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6 July 2018

Salmonellosis: host immune responses and bacterial virulence determinants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

A lymphotoxin-beta-specific receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Characterization of the mouse lymphotoxin-beta gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface

1 reference

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6 July 2018

Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages

1 reference

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6 July 2018

Cloning and expression analysis of the murine lymphotoxin beta gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

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Effect of anti-tumor necrosis factor alpha antibodies on histopathology of primary Salmonella infections

1 reference

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Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Exogenous tumor necrosis factor alpha and interleukin-1 alpha increase resistance to Salmonella typhimurium: efficacy is influenced by the Ity and Lps loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Active Oxygen Species and the Functions of Phagocytic Leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 of the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Constitutive synthesis of tumor necrosis factor in the thymus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

An endotoxin-induced serum factor that causes necrosis of tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

6 July 2018

Membrane lymphotoxin contributes to anti-leishmanial immunity by controlling structural integrity of lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

27 October 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

27 October 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

27 October 2018

Expression of alpha(4)beta(7) integrin defines a distinct pathway of lymphoid progenitors committed to T cells, fetal intestinal lymphotoxin producer, NK, and dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

27 October 2018

Immune responsiveness of lymphotoxin-alpha-deficient mice: two reconstitution models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

27 October 2018

The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

27 October 2018

Tandem arrangement of genes coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

27 October 2018

Tumour necrosis factor and lymphotoxin genes map close to H–2D in the mouse major histocompatibility complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139867

9 December 2018

Gene profiling approach in the analysis of lymphotoxin and TNF deficiencies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complementation of lymphotoxin deficiency with LIGHT, a newly discovered TNF family member, for the restoration of secondary lymphoid structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic Effect of Lymphocyte-Antigen Interaction in Delayed Hypersensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphocyte Cytotoxicity in vitro: Activation and Release of a Cytotoxic Factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal organisation of the splenic marginal zone and the correlated leukocytosis in lymphotoxin-alpha and tumor necrosis factor alpha double deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin induces expression of type II phospholipase A2 in macrophages during acute lung injury in guinea pigs: involvement of TNF-alpha in lipopolysaccharide-induced type II phospholipase A2 synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with a targeted mutation in lymphotoxin-alpha exhibit enhanced tumor growth and metastasis: impaired NK cell development and recruitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developing Lymph Nodes Collect CD4 + CD3 − LTβ + Cells That Can Differentiate to APC, NK Cells, and Follicular Cells but Not T or B Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reticular fibroblasts in peripheral lymphoid organs identified by a monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunity to intracellular bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manipulation of transgenes by site-specific recombination: use of Cre recombinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Characteristics of murine chromosome 17 containing three tumor necrosis factor family genes, including the gene of the transmembrane subunit of lymphotoxin]

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers

1 reference

https://pubmed.ncbi.nlm.nih.gov/12446781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.22.24.8626-8634.2002

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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