Drug discovery and development for ageing: opportunities and challenges (Q34402737)

1 August 2017

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title

Drug discovery and development for ageing: opportunities and challenges (English)

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1 August 2017

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William J Evans

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1 August 2017

language of work or name

English

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publication date

1 January 2011

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Philosophical Transactions of the Royal Society B

1 August 2017

published in

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1 August 2017

volume

366

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1 August 2017

issue

1561

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1 August 2017

page(s)

113-119

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Excessive loss of skeletal muscle mass in older adults with type 2 diabetes

1 August 2017

cites work

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The danger of weight loss in the elderly

6 July 2018

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Functional outcomes for clinical trials in frail older persons: time to be moving

6 July 2018

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Low nutrient intake is an essential component of frailty in older persons

6 July 2018

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Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study

6 July 2018

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Skeletal muscle lipid and its association with insulin resistance: what is the role for exercise?

6 July 2018

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6 July 2018

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Vitamin D in the aging musculoskeletal system: an authentic strength preserving hormone

6 July 2018

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Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care

6 July 2018

1 reference

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Frailty--the search for underlying causes

6 July 2018

1 reference

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Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam

6 July 2018

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Physiological limitations and age

6 July 2018

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Orexigenic and anabolic agents

6 July 2018

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Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study

6 July 2018

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Frailty in older adults: evidence for a phenotype

6 July 2018

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Nutritional management in long-term care: development of a clinical guideline. Council for Nutritional Strategies in Long-Term Care

6 July 2018

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Epidemiology of sarcopenia among the elderly in New Mexico

6 July 2018

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Exercise training and nutritional supplementation for physical frailty in very elderly people

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001314

Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability

6 July 2018

1 reference

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6 July 2018

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Strength conditioning in older men: skeletal muscle hypertrophy and improved function

6 July 2018

1 reference

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Physiology and complications of bed rest

6 July 2018

1 reference

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A prospective study of outcome from protein-energy malnutrition in nursing home residents

6 July 2018

1 reference

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Longitudinal changes in basal metabolism in man

6 July 2018

1 reference

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Anorexia and weight loss in older persons

6 July 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

Editorial: Megestrol acetate use for weight gain should be carefully considered

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

21 January 2018

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Chekhov's "The Butterfly".

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

The healthcare costs of sarcopenia in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

Intentional and unintentional weight loss increase bone loss and hip fracture risk in older women

21 January 2018

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Loss of independence in activities of daily living in older adults hospitalized with medical illnesses: increased vulnerability with age.

21 January 2018

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Protein-energy undernutrition among elderly hospitalized patients: a prospective study

21 January 2018

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Longitudinal changes in body composition in older men and women: role of body weight change and physical activity

21 January 2018

1 reference

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Sarcopenic Obesity Predicts Instrumental Activities of Daily Living Disability in the Elderly

27 October 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

Fat mass rather than muscle strength is the major determinant of physical function and disability in postmenopausal women younger than 75 years of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2010.0287

Physical disability and muscular strength in relation to obesity and different body composition indexes in a sample of healthy elderly women

21 January 2018

1 reference

12 December 2020

Changes in cardiac output with age

1 reference

12 December 2020

Sarcopenia in premenopausal and postmenopausal women with osteopenia, osteoporosis and normal bone mineral density

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12 December 2020

Inflammatory Markers and Loss of Muscle Mass (Sarcopenia) and Strength

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12 December 2020

Effect of 10 days of bed rest on skeletal muscle in healthy older adults

1 reference

12 December 2020

Functional impact of 10 days of bed rest in healthy older adults

1 reference

12 December 2020

Sarcopenia is related to physical functioning and leg strength in middle-aged women

1 reference

12 December 2020

A role for sarcopenia in late-life osteoporosis

1 reference

12 December 2020

Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study

1 reference

12 December 2020

Identifiers

DOI

10.1098/RSTB.2010.0287

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1 August 2017

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1 August 2017

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