Meta-analysis derived (MAD) transcriptome of psoriasis defines the "core" pathogenesis of disease (Q34408063)

2 August 2017

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Meta-analysis derived (MAD) transcriptome of psoriasis defines the "core" pathogenesis of disease (English)

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2 August 2017

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Suyan Tian

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Ali Jabbari

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Michelle A Lowes

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Mayte Suárez-Fariñas

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2 August 2017

James G Krueger

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2 August 2017

Katherine Li

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2 August 2017

Carrie Brodmerkel

series ordinal

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2 August 2017

language of work or name

English

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publication date

5 September 2012

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2 August 2017

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

e44274

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Creative Commons Attribution 4.0 International

2 August 2017

start time

5 September 2012

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis

6 July 2018

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Combined use of laser capture microdissection and cDNA microarray analysis identifies locally expressed disease-related genes in focal regions of psoriasis vulgaris skin lesions

6 July 2018

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Psoriasis and other complex trait dermatoses: from Loci to functional pathways

6 July 2018

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A subset of methylated CpG sites differentiate psoriatic from normal skin.

6 July 2018

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Transcriptional profiling of psoriasis using RNA-seq reveals previously unidentified differentially expressed genes.

6 July 2018

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Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities

6 July 2018

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The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans

6 July 2018

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Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis

6 July 2018

1 reference

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Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

6 July 2018

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Resolved psoriasis lesions retain expression of a subset of disease-related genes

6 July 2018

1 reference

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Comparison study of microarray meta-analysis methods.

6 July 2018

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Identification of TNF-related apoptosis-inducing ligand and other molecules that distinguish inflammatory from resident dendritic cells in patients with psoriasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions

6 July 2018

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Evaluation of the psoriasis transcriptome across different studies by gene set enrichment analysis (GSEA).

6 July 2018

1 reference

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Activation of PPARbeta/delta causes a psoriasis-like skin disease in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Global gene expression analysis reveals evidence for decreased lipid biosynthesis and increased innate immunity in uninvolved psoriatic skin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Type I interferon: potential therapeutic target for psoriasis?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Meta-analysis combines affymetrix microarray results across laboratories

6 July 2018

1 reference

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TAM receptors are pleiotropic inhibitors of the innate immune response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Meta-analysis of microarray results: challenges, opportunities, and recommendations for standardization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

The psoriatic transcriptome closely resembles that induced by interleukin-1 in cultured keratinocytes: dominance of innate immune responses in psoriasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Macrophages and dendritic cells use different Axl/Mertk/Tyro3 receptors in clearance of apoptotic cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Comparing independent microarray studies: the case of human embryonic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Differential expression of phosphorylated NF-kappaB/RelA in normal and psoriatic epidermis and downregulation of NF-kappaB in response to treatment with etanercept

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

6 July 2018

1 reference

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Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Meta-analysis: formulating, evaluating, combining, and reporting

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Meta-analysis in clinical trials

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Gone but not forgotten: lesional memory in psoriatic skin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Vectorized Radviz and its application to multiple cluster datasets

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Diabetic modifier QTLs in F(2) intercrosses carrying homozygous transgene of TGF-beta

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Increased expression of Wnt5a in psoriatic plaques.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Expression of the serine protease DESC1 correlates directly with normal keratinocyte differentiation and inversely with head and neck squamous cell carcinoma progression

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Activator protein 1 DNA binding activity is decreased in lesional psoriatic skin compared with nonlesional psoriatic skin.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Psoriasis genomics: analysis of proinflammatory (type 1) gene expression in large plaque (Western) and small plaque (Asian) psoriasis vulgaris

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Combining multiple microarray studies and modeling interstudy variation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Differentially expressed genes in human peripheral blood as potential markers for statin response

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Expression and Localization of Peroxisome Proliferator-Activated Receptors and Nuclear Factor κB in Normal and Lesional Psoriatic Skin

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434204

Plasma vitamin B12 binding proteins correlate with disease activity in patients with rheumatoid arthritis

9 December 2018

1 reference

12 December 2020

Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

1 reference

12 December 2020

The role of Bach2 in nucleic acid-triggered antiviral innate immune responses

1 reference

12 December 2020

Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling

1 reference

12 December 2020

Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

1 reference

12 December 2020

A cross-study comparison of gene expression studies for the molecular classification of lung cancer

1 reference

12 December 2020

Risk of Myocardial Infarction in Patients With Psoriasis

1 reference

12 December 2020

Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies

1 reference

12 December 2020

PPAR-gamma gene polymorphisms and psoriatic arthritis

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0044274

Identifiers

DOI

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2 August 2017

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2 August 2017

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