A novel Mtd splice isoform is responsible for trophoblast cell death in pre-eclampsia (Q34404307)

2 August 2017

title

A novel Mtd splice isoform is responsible for trophoblast cell death in pre-eclampsia (English)

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2 August 2017

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Soleymanlou N

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2 August 2017

Wu Y

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2 August 2017

Wang JX

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2 August 2017

Todros T

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2 August 2017

Ietta F

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2 August 2017

Jurisicova A

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2 August 2017

Post M

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2 August 2017

Caniggia I

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2 August 2017

publication date

1 May 2005

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Cell Death & Differentiation

2 August 2017

published in

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

441-452

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A study of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies

2 August 2017

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Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall

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Differences in apoptotic susceptibility of cytotrophoblasts and syncytiotrophoblasts in normal pregnancy to those complicated with preeclampsia and intrauterine growth restriction

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Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

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Focal adhesion kinase is a key mediator of human trophoblast development

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Hypertension in pregnancy

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7 January 2021

Placental debris, oxidative stress and pre-eclampsia

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Is oxidative stress the link in the two-stage model of pre-eclampsia?

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Trophoblast deportation and the maternal inflammatory response in pre-eclampsia

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Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta

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BCL-2 family members and the mitochondria in apoptosis

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Tissue-specific Bcl-2 protein partners in apoptosis: An ovarian paradigm

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Expression of BCL-2, BAX and BAK in the Trophoblast Layer of the Term Human Placenta: a Unique Model of Apoptosis within a Syncytium

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7 January 2021

Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression

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Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation

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Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members

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7 January 2021

Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL

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7 January 2021

A splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitro

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7 January 2021

Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia.

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Endoglin regulates trophoblast differentiation along the invasive pathway in human placental villous explants

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Role of Mtd/Bok in normal and neoplastic B-cell development in the bursa of Fabricius

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Increased placental apoptosis in pregnancies complicated by preeclampsia

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Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3)

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Regulation of Human Placental Development by Oxygen Tension

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7 January 2021

Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia

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7 January 2021

Role of Bag-1 in the survival and proliferation of the cytokine-dependent lymphocyte lines, Ba/F3 and Nb2.

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Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

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7 January 2021

BAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrest

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Expression of Bcl-XS alters cytokinetics and decreases clonogenic survival in K12 rat colon carcinoma cells

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Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor

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7 January 2021

Selective overexpression of the hypoxia-inducible transcription factor, HIF-2alpha, in placentas from women with preeclampsia

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7 January 2021

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

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7 January 2021

BOK and NOXA are essential mediators of p53-dependent apoptosis

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7 January 2021

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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7 January 2021

A rapid and simple method for the isolation of apoptotic DNA fragments.

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401593

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2 August 2017

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