Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody (Q34391211)

1 August 2017

title

Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody (English)

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1 August 2017

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Kelly R Bales

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1 August 2017

Eleni T Tzavara

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1 August 2017

Su Wu

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1 August 2017

Mark R Wade

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1 August 2017

Frank P Bymaster

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1 August 2017

Steven M Paul

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1 August 2017

George G Nomikos

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1 August 2017

language of work or name

English

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publication date

23 February 2006

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full work available at URL

1 August 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378188

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published in

Journal of Clinical Investigation

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1 August 2017

volume

116

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1 August 2017

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1 August 2017

page(s)

825-832

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Regulation of NMDA receptor trafficking by amyloid-beta

1 August 2017

cites work

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Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

6 July 2018

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Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice

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Alzheimer's disease is a synaptic failure

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

6 July 2018

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6 July 2018

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Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

6 July 2018

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6 July 2018

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beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

6 July 2018

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

6 July 2018

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Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

6 July 2018

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6 July 2018

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Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

6 July 2018

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Choline: High-Affinity Uptake by Rat Brain Synaptosomes

6 July 2018

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Measurement of acetylcholine and choline in brain by HPLC with electrochemical detection

6 July 2018

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Regulatory changes in presynaptic cholinergic function assessed in rapid autopsy material from patients with Alzheimer disease: implications for etiology and therapy

6 July 2018

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The novel 5-HT1A receptor antagonist (S)-UH-301 prevents (R)-8-OH-DPAT-induced decrease in interstitial concentrations of serotonin in the rat hippocampus

6 July 2018

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Choline metabolism as a basis for the selective vulnerability of cholinergic neurons

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1378188

Sodium-dependent high affinity choline uptake: a regulatory step in the synthesis of acetylcholine

6 July 2018

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Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency.

6 July 2018

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Regulation of choline transporter surface expression and phosphorylation by protein kinase C and protein phosphatase 1/2A.

27 October 2018

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Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

27 October 2018

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1378188

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1378188

Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1378188

The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1378188

Aβ Deposition Is Associated with Neuropil Changes, but not with Overt Neuronal Loss in the Human Amyloid Precursor Protein V717F (PDAPP) Transgenic Mouse

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1378188

Conditioned and unconditioned stimuli increase frontal cortical and hippocampal acetylcholine release: effects of novelty, habituation, and fear.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1378188

Correlation between Abetax-40-, Abetax-42-, and Abetax-43-containing amyloid plaques and cognitive decline

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16498501

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neural inputs into the nucleus basalis of the substantia innominata (Ch4) in the rhesus monkey

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16498501

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI27120

1 reference

1 August 2017

1 reference

1 August 2017

1 reference