Intronic RNAs mediate EZH2 regulation of epigenetic targets (Q34278668)

1 August 2017

title

Intronic RNAs mediate EZH2 regulation of epigenetic targets (English)

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1 August 2017

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1 August 2017

Antonio Gómez

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Anna Portela

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Sònia Guil

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1 August 2017

Marta Soler

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1 August 2017

Jordi Carrère

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Elena Fonalleras

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Alberto Villanueva

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1 August 2017

publication date

3 June 2012

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Nature Structural & Molecular Biology

1 August 2017

published in

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1 August 2017

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1 August 2017

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1 August 2017

page(s)

664-670

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Polycomb silencers control cell fate, development and cancer

1 August 2017

cites work

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Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.

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Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.

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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

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Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene

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Critical association of ncRNA with introns

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Genome mapping and expression analyses of human intronic noncoding RNAs reveal tissue-specific patterns and enrichment in genes related to regulation of transcription

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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

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Control of developmental regulators by Polycomb in human embryonic stem cells

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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells

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Enhanced SMYD3 expression is essential for the growth of breast cancer cells

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Aberrations of EZH2 in cancer

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A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

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Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor

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Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

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hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing

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Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes

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21 January 2018

Identifiers

DOI

10.1038/NSMB.2315

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1 August 2017

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