Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs (Q34162438)

31 July 2017

1 reference

title

Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs (English)

1 reference

31 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292505

23 November 2024

drug design

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292505

23 November 2024

Wolfgang Löscher

1 reference

31 July 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21292505

23 November 2024

publication date

2 February 2011

1 reference

full work available at URL

31 July 2017

http://www.seizure-journal.com/article/S1059131111000124/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21292505

https://api.elsevier.com/content/article/PII:S1059131111000124?httpAccept=text/xml

23 November 2024

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

https://api.elsevier.com/content/article/PII:S1059131111000124?httpAccept=text/plain

23 November 2024

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Seizure-European Journal of Epilepsy

23 November 2024

published in

1 reference

31 July 2017

1 reference

31 July 2017

1 reference

31 July 2017

page(s)

359-368

1 reference

Key factors in the discovery and development of new antiepileptic drugs

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Genetic animal models of epilepsy

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Overview of the Current Animal Models for Human Seizure and Epileptic Disorders

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Antiepileptic drug development: II. Anticonvulsant drug screening

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Kindling: basic mechanisms and clinical validity

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Refractory epilepsy: mechanisms and solutions

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Development of new antiepileptic drugs: challenges, incentives, and recent advances

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Lamotrigine treatment during amygdala-kindled seizure development fails to inhibit seizures and diminishes subsequent anticonvulsant efficacy

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Experimental and clinical evidence for loss of effect (tolerance) during prolonged treatment with antiepileptic drugs

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Neurodevelopmental disorders as a cause of seizures: neuropathologic, genetic, and mechanistic considerations.

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Animal models of intractable epilepsy

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Kindling as a model of drug-resistant partial epilepsy: selection of phenytoin-resistant and nonresistant rats

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

The pharmacokinetics of antiepileptic drugs in rats: consequences for maintaining effective drug levels during prolonged drug administration in rat models of epilepsy

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Striking differences in individual anticonvulsant response to phenobarbital in rats with spontaneous seizures after status epilepticus.

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Drug resistance in brain diseases and the role of drug efflux transporters.

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Use of epileptic animals for adverse effect testing

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Responses to NMDA receptor antagonists altered by epileptogenesis

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Kindling Increases the Sensitivity of Rats to Adverse Effects of Certain Antiepileptic Drugs

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation?

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Models for epilepsy and epileptogenesis: report from the NIH workshop, Bethesda, Maryland.

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

23 November 2024

Posttraumatic epilepsy

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Prevention or Modification of Epileptogenesis after Brain Insults: Experimental Approaches and Translational Research

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Animal models of epilepsy for the development of antiepileptogenic and disease-modifying drugs. A comparison of the pharmacology of kindling and post-status epilepticus models of temporal lobe epilepsy

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Drug treatment of epilepsy in the century of the ILAE: the second 50 years, 1959-2009.

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Progress report on new antiepileptic drugs: a summary of the Ninth Eilat Conference (EILAT IX).

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

What is an epileptic seizure? Unifying definitions in clinical practice and animal research to develop novel treatments

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

Modern management of epilepsy: a practical approach

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions.

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

The neurobiology of antiepileptic drugs

23 November 2024

1 reference

https://api.crossref.org/works/10.1016/J.SEIZURE.2011.01.003

23 November 2024

Identifiers

DOI

1 reference

31 July 2017

1 reference