Inhibition of human factor VIIIa by anti-A2 subunit antibodies (Q34151336)

31 July 2017

title

Inhibition of human factor VIIIa by anti-A2 subunit antibodies (English)

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31 July 2017

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P Lollar

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31 July 2017

E T Parker

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31 July 2017

J E Curtis

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31 July 2017

S L Helgerson

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31 July 2017

L W Hoyer

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31 July 2017

M E Scott

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31 July 2017

D Scandella

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31 July 2017

language of work or name

English

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publication date

1 June 1994

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Journal of Clinical Investigation

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

2497-2504

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A recombinant factor VIII A2 domain polypeptide quantitatively neutralizes human inhibitor antibodies that bind to A2

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Structure of human factor VIII

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivity

5 July 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

5 July 2018

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Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders

5 July 2018

1 reference

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Complete cDNA and derived amino acid sequence of human factor V

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Localization of epitopes for human factor VIII inhibitor antibodies by immunoblotting and antibody neutralization

5 July 2018

1 reference

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Identification of a F.VIII epitope recognized by a human hemophilic inhibitor

5 July 2018

1 reference

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Epitope mapping of human factor VIII inhibitor antibodies by deletion analysis of factor VIII fragments expressed in Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

pH-dependent denaturation of thrombin-activated porcine factor VIII.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Synthetic factor VIII peptides with amino acid sequences contained within the C2 domain of factor VIII inhibit factor VIII binding to phosphatidylserine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Deletion analysis of recombinant human factor V. Evidence for a phosphatidylserine binding site in the second C-type domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

The active site of factor IXa is located far above the membrane surface and its conformation is altered upon association with factor VIIIa. A fluorescence study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Binding of factor VIIIa and factor VIII to factor IXa on phospholipid vesicles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

A soluble recombinant factor VIII fragment containing the A2 domain binds to some human anti-factor VIII antibodies that are not detected by immunoblotting.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Epitope mapping of human factor VIII inhibitor antibodies by site-directed mutagenesis of a factor VIII polypeptide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

A simple method for the preparation of homogeneous phospholipid vesicles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-Sepharose

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Isolation and characterization of thrombin-activated human factor VIII.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Structural basis for the decreased procoagulant activity of human factor VIII compared to the porcine homolog.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=294465

Reaction Sequence of Blood Coagulation

28 October 2018

1 reference

12 December 2020

Letter: A more uniform measurement of factor VIII inhibitors

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12 December 2020

Free energy diagrams and concentration profiles for enzyme-catalyzed reactions

1 reference

12 December 2020

Regulation of plasminogen activator secretion in mouse peritoneal macrophages. I. - Role of serum studied by a new spectrophotometric assay for plasminogen activators

1 reference

12 December 2020

Subunit structure of thrombin-activated porcine factor VIII

1 reference

12 December 2020

Human factor VIIIa subunit structure. Reconstruction of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit

1 reference

12 December 2020

Intrinsic pathway activation of factor X and its activation peptide-deficient derivative, factor Xdes-143-191

1 reference

12 December 2020

The role of phospholipid and factor VIIIa in the activation of bovine factor X

1 reference

12 December 2020

Stabilization of thrombin-activated porcine factor VIII:C by factor IXa phospholipid

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI117259

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31 July 2017

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31 July 2017

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