Calcium, calcineurin, and the control of transcription (Q34092392)

31 July 2017

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title

Calcium, calcineurin, and the control of transcription (English)

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31 July 2017

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Crabtree GR

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31 July 2017

language of work or name

English

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publication date

28 November 2000

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Journal of Biological Chemistry

31 July 2017

published in

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31 July 2017

volume

276

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31 July 2017

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31 July 2017

page(s)

2313-2316

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Identification of a putative regulator of early T cell activation genes

31 July 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.R000024200

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

21 January 2018

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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

21 January 2018

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

21 January 2018

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Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells

21 January 2018

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A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor

21 January 2018

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Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation

21 January 2018

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The mechanism of action of cyclosporin A and FK506

21 January 2018

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Isolation of mutant T lymphocytes with defects in capacitative calcium entry

21 January 2018

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Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for the physiological roles of CRAC channels.

21 January 2018

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Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression

21 January 2018

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The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

21 January 2018

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Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction

21 January 2018

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Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity

21 January 2018

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Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

21 January 2018

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Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp)

21 January 2018

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NF-AT components define a family of transcription factors targeted in T-cell activation

21 January 2018

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Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

21 January 2018

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Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

21 January 2018

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Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

21 January 2018

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Contingent genetic regulatory events in T lymphocyte activation

21 January 2018

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p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells

21 January 2018

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Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc

21 January 2018

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Nuclear Accumulation of NFAT4 Opposed by the JNK Signal Transduction Pathway

21 January 2018

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Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

21 January 2018

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Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene

21 January 2018

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Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes

21 January 2018

1 reference

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Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin

21 January 2018

1 reference

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Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory.

21 January 2018

1 reference

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L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

21 January 2018

1 reference

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Calcineurin controls inositol 1,4,5-trisphosphate type 1 receptor expression in neurons.

21 January 2018

1 reference

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The transcription factor NF-ATc is essential for cardiac valve formation

21 January 2018

1 reference

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Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

21 January 2018

1 reference

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A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

21 January 2018

1 reference

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Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases

21 January 2018

1 reference

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Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

Tcn1p/Crz1p, a calcineurin-dependent transcription factor that differentially regulates gene expression inSaccharomyces cerevisiae

21 January 2018

1 reference

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Yeast calcineurin regulates nuclear localization of the Crz1p transcription factor through dephosphorylation

21 January 2018

1 reference

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DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

21 January 2018

1 reference

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Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans

21 January 2018

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Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes

21 January 2018

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Cain, a novel physiologic protein inhibitor of calcineurin

21 January 2018

1 reference

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A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange

21 January 2018

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Inhibition of calcineurin phosphatase activity by a calcineurin B homologous protein

21 January 2018

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A viral mechanism for inhibition of the cellular phosphatase calcineurin.

21 January 2018

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Association of protein kinase A and protein phosphatase 2B with a common anchoring protein

21 January 2018

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A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling

21 January 2018

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A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart

21 January 2018

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Molecular cloning of a novel thyroid hormone-responsive gene, ZAKI-4, in human skin fibroblasts

21 January 2018

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FK506 inhibits antigen receptor-mediated induction of c-rel in B and T lymphoid cells

21 January 2018

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Activation of early gene expression in T lymphocytes by Oct-1 and an inducible protein, OAP40.

21 January 2018

1 reference

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Jun family members are controlled by a calcium-regulated, cyclosporin A-sensitive signaling pathway in activated T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

Neuronal activity-dependent cell survival mediated by transcription factor MEF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R000024200

21 January 2018

Identifiers

DOI

10.1074/JBC.R000024200

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31 July 2017

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