Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus (Q34082576)

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English	Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus (English)

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Europe PubMed Central

PubMed publication ID

30 July 2017

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Camillo Ricordi

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C Ricordi

6

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7

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J F Habener

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Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

J Seufert

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

T J Kieffer

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

C A Leech

3

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Europe PubMed Central

PubMed publication ID

30 July 2017

G G Holz

4

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Europe PubMed Central

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30 July 2017

W Moritz

5

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30 July 2017

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publication date

1 February 1999

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Europe PubMed Central

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30 July 2017

The Journal of Clinical Endocrinology and Metabolism

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Europe PubMed Central

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30 July 2017

84

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Europe PubMed Central

PubMed publication ID

30 July 2017

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

670-676

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Europe PubMed Central

PubMed publication ID

30 July 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2927866/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin inhibits insulin secretion by activation of phosphodiesterase 3B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Insulin occludes leptin activation of ATP-sensitive K+ channels in rat CRI-G1 insulin secreting cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Identification of SOCS-3 as a potential mediator of central leptin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Role of tyrosine phosphorylation in leptin activation of ATP-sensitive K+ channels in the rat insulinoma cell line CRI-G1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Effects of leptin on insulin secretion from isolated rat pancreatic islets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin activates ATP-sensitive potassium channels in the rat insulin-secreting cell line, CRI-G1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin: A Potent Inhibitor of Insulin Secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin Stimulates Insulin Secretion and Synthesis in HIT-T 15 Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Direct Stimulation of Basal Insulin Secretion by Physiological Concentrations of Leptin in Pancreatic β Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Insulin Stimulates Both Leptin Secretion and Production by Rat White Adipose Tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin Inhibits Insulin Secretion and Reduces Insulin mRNA Levels in Rat Isolated Pancreatic Islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin constrains acetylcholine-induced insulin secretion from pancreatic islets of ob/ob mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin suppresses basal insulin secretion from rat pancreatic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Weight Change and Diabetes Incidence: Findings from a National Cohort of US Adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Risk of noninsulin dependent diabetes mellitus conferred by obesity and central adiposity in different ethnic groups: A comparative analysis between Asian Indians, Mexican Americans and Whites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin expression and action: new experimental paradigms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Science, medicine, and the future. Non-insulin dependent diabetes mellitus: the gathering storm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

The endocrinology of obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Adipogenesis and obesity: rounding out the big picture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Insulin and cortisol promote leptin production in cultured human fat cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin receptors expressed on pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Reflections on STAT3, STAT5, and STAT6 as fat STATs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

The incretin notion and its relevance to diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Increased intracellular cyclic AMP levels suppress the mitogenic responses of human astrocytoma cells to growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Insulinotropic hormone glucagon-like peptide-I(7-37) stimulation of proinsulin gene expression and proinsulin biosynthesis in insulinoma beta TC-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

5 July 2018

Time trends in obesity: an epidemiological perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

28 October 2018

The epidemiology of obesity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2927866

28 October 2018

What’s in a Name? In Search of Leptin’s Physiologic Role1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of GLP-I and leptin at rat pancreatic B-cells: effects on insulin secretion and signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin inhibition of insulin secretion from isolated human islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlates of body weight in the 1994 National Population Health Survey

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonistic and antagonistic effects of cholera toxin on human B lymphocyte proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species differences in the induction of time-dependent potentiation of insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do leptin receptors play a functional role in the endocrine pancreas?

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved human islet isolation using a new enzyme blend, liberase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10022436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/JC.84.2.670

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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