Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters (Q34061721)

30 July 2017

title

Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters (English)

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30 July 2017

Alessandra Picollo

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Mattia Malvezzi

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30 July 2017

Jon C D Houtman

series ordinal

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30 July 2017

Alessio Accardi

series ordinal

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30 July 2017

language of work or name

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8 November 2009

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Nature Structural & Molecular Biology

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

1294-1301

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Intracellular Proton-Transfer Mutants in a CLC Cl − /H + Exchanger

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

A competitive inhibitor traps LeuT in an open-to-out conformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

A provisional transport mechanism for a chloride channel-type Cl-/H+ exchanger

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Intracellular proton regulation of ClC-0

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

CLC Cl /H+ transporters constrained by covalent cross-linking

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

The mechanism of fast-gate opening in ClC-0.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Ligand binding and activation in a prokaryotic cyclic nucleotide-modulated channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Structural and thermodynamic properties of selective ion binding in a K+ channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Uncoupling and turnover in a Cl-/H+ exchange transporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Energetics of ligand-induced conformational flexibility in the lactose permease of Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Synergism between halide binding and proton transport in a CLC-type exchanger.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

ClC chloride channels viewed through a transporter lens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Ion-binding properties of the ClC chloride selectivity filter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Separate ion pathways in a Cl-/H+ exchanger

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Side-dependent inhibition of a prokaryotic ClC by DIDS.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Escherichia coli glutamate- and arginine-dependent acid resistance systems increase internal pH and reverse transmembrane potential

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

A cyclic nucleotide modulated prokaryotic K+ channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Gating competence of constitutively open CLC-0 mutants revealed by the interaction with a small organic Inhibitor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Gating the selectivity filter in ClC chloride channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Gating mechanism of BK (Slo1) channels: so near, yet so far

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Homology modeling of the cation binding sites of Na+K+-ATPase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Interaction of hydrophobic anions with the rat skeletal muscle chloride channel ClC-1: effects on permeation and gating

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Chloride dependence of hyperpolarization-activated chloride channel gates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Nonequilibrium gating and voltage dependence of the ClC-0 Cl- channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Rapid measurement of binding constants and heats of binding using a new titration calorimeter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

A 35Cl and 37Cl NMR study of chloride binding to the erythrocyte anion transport protein

5 July 2018

1 reference

Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels

21 January 2018

1 reference

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes.

21 January 2018

1 reference

CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and Physiology

21 January 2018

1 reference

Uncoupling of a CLC Cl-/H+ exchange transporter by polyatomic anions.

21 January 2018

1 reference

On the value of c: can low affinity systems be studied by isothermal titration calorimetry?

21 January 2018

1 reference

A biological role for prokaryotic ClC chloride channels

21 January 2018

1 reference

Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels

21 January 2018

1 reference

Electrostatics of ion stabilization in a ClC chloride channel homologue from Escherichia coli

21 January 2018

1 reference

Two physically distinct pores in the dimeric ClC-0 chloride channel.

21 January 2018

1 reference

Gating of the voltage-dependent chloride channel CIC-0 by the permeant anion

21 January 2018

1 reference

Substrate-induced Conformational Fit and Headpiece Closure in the Ca2+ATPase (SERCA)

21 January 2018

1 reference

Characterization of Ca2+ ATPase residues involved in substrate and cation binding

21 January 2018

1 reference

Crystal structures of Ca2+-ATPase in various physiological states.

21 January 2018

1 reference

Determinants of anion-proton coupling in mammalian endosomal CLC proteins

21 January 2018

1 reference

Analysis of a protein region involved in permeation and gating of the voltage-gated Torpedo chloride channel ClC-0

21 January 2018

1 reference

Residues important for nitrate/proton coupling in plant and mammalian CLC transporters

21 January 2018

1 reference

Conversion of the 2 Cl(-)/1 H+ antiporter ClC-5 in a NO3(-)/H+ antiporter by a single point mutation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920496

The nitrate/proton antiporter AtCLCa mediates nitrate accumulation in plant vacuoles

28 October 2018

1 reference

A bacterial arginine-agmatine exchange transporter involved in extreme acid resistance

21 January 2018

1 reference

Isothermal titration calorimetry at very low c

31 March 2020

1 reference

S-glutathionylation of IRF3 regulates IRF3-CBP interaction and activation of the IFN beta pathway

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.1704

1 reference

Dimensions Publication ID

30 July 2017

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1 reference

30 July 2017

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