Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide (Q34065528)

30 July 2017

title

Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide (English)

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30 July 2017

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30 July 2017

David Fernández-Ramos

object named as

David Fernández-Ramos

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Josep Julve

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José M Mato

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Shelly C Lu

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30 July 2017

Marta Varela-Rey

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30 July 2017

Nuria Martínez-López

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30 July 2017

Nieves Embade

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30 July 2017

Diego F Calvisi

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30 July 2017

Aswhin Woodhoo

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30 July 2017

Juan Rodríguez

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30 July 2017

Mario F Fraga

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30 July 2017

Elisabeth Rodríguez-Millán

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30 July 2017

Itziar Frades

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30 July 2017

Luís Torres

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30 July 2017

Zigmund Luka

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30 July 2017

Conrad Wagner

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30 July 2017

M Luz Martínez-Chantar

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30 July 2017

language of work or name

English

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publication date

1 July 2010

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

105-114

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Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells

30 July 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921576

Glycine N-methyltransferase and regulation of S-adenosylmethionine levels

28 July 2018

1 reference

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Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation.

28 July 2018

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Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues

28 July 2018

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Sirt1 protects against high-fat diet-induced metabolic damage

28 July 2018

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Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

28 July 2018

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Methionine metabolism and liver disease

28 July 2018

1 reference

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Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice

28 July 2018

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Role of S-adenosyl-L-methionine in liver health and injury

28 July 2018

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A glycine N-methyltransferase knockout mouse model for humans with deficiency of this enzyme

28 July 2018

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Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein

28 July 2018

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Towards a proteome-scale map of the human protein–protein interaction network

28 July 2018

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Alcoholic fatty liver: its pathogenesis and mechanism of progression to inflammation and fibrosis

28 July 2018

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Methylation of nicotinamide with soluble enzyme system from rat liver

28 July 2018

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Glycine N -methyltransferase deficiency: a new patient with a novel mutation

28 July 2018

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Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

28 July 2018

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High-performance capillary electrophoretic method for the quantification of 5-methyl 2'-deoxycytidine in genomic DNA: application to plant, animal and human cancer tissues

28 July 2018

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Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921576

Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia

28 July 2018

1 reference

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Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation

28 July 2018

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CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

28 July 2018

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A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders

28 July 2018

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Characterization of glycine-N-methyltransferase-gene expression in human hepatocellular carcinoma

28 July 2018

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Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation.

28 July 2018

1 reference

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Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility

28 October 2018

1 reference

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Mechanisms of disease progression in nonalcoholic fatty liver disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921576

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

28 October 2018

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Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine

28 October 2018

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L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine

28 October 2018

1 reference

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Nicotinamide is a potent inhibitor of proinflammatory cytokines

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2921576

Steroid and sterol 7-hydroxylation: ancient pathways

28 October 2018

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S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase

28 October 2018

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12 December 2020

Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity

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12 December 2020

Hepatocellular carcinoma in GNMT-/- mice

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12 December 2020

Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma

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12 December 2020

Effect of nicotinamide treatment on the residual insulin secretion in type 1 (insulin-dependent) diabetic patients

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12 December 2020

A sensitive new method for rapid detection of abnormal methylation patterns in global DNA and within CpG islands

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12 December 2020

Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity

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12 December 2020

Identifiers

DOI

10.1002/HEP.23639

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30 July 2017

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30 July 2017

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