Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury (Q34056196)

30 July 2017

title

Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury (English)

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30 July 2017

1 reference

1 reference

Eric J Huang

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Bing Na

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30 July 2017

Zhiming Huang

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30 July 2017

Qian Wang

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30 July 2017

Zhongxia Qi

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30 July 2017

Yongjun Tian

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30 July 2017

Cheng-Chan Lu

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30 July 2017

Jingwei Yu

1 reference

30 July 2017

Martha A Hanes

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30 July 2017

Sanjay Kakar

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30 July 2017

J-H James Ou

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30 July 2017

Limin Liu

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30 July 2017

T S Benedict Yen

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30 July 2017

language of work or name

English

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publication date

12 October 2011

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

e26240

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Creative Commons Attribution 4.0 International

30 July 2017

start time

12 October 2011

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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28 July 2018

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The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis

28 July 2018

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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

28 July 2018

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Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress

28 July 2018

1 reference

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Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia

28 July 2018

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28 July 2018

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28 July 2018

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XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

28 July 2018

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High prevalence of hepatitis B virus pre-s mutant in countries where it is endemic and its relationship with genotype and chronicity

28 July 2018

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Molecular viral oncology of hepatocellular carcinoma

28 July 2018

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Caught up in a Wnt storm: Wnt signaling in cancer

28 July 2018

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Cellular vacuolization and apoptosis induced by hepatitis B virus large surface protein

28 July 2018

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Hypermodification and immune escape of an internally deleted middle-envelope (M) protein of frequent and predominant hepatitis B virus variants

28 July 2018

1 reference

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Enhancement of hepatitis B virus replication by its X protein in transgenic mice

28 July 2018

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

28 July 2018

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Identification of a pre-S2 mutant in hepatocytes expressing a novel marginal pattern of surface antigen in advanced diseases of chronic hepatitis B virus infection

28 July 2018

1 reference

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Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

28 July 2018

1 reference

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Immune pathogenesis of hepatocellular carcinoma.

28 July 2018

1 reference

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Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME.

28 July 2018

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Intracellular retention of surface protein by a hepatitis B virus mutant that releases virion particles

28 July 2018

1 reference

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Dysregulated surface gene expression from disrupted hepatitis B virus genomes.

28 July 2018

1 reference

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High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192172

High-level hepatitis B virus replication in transgenic mice

28 July 2018

1 reference

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Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice

28 July 2018

1 reference

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Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192172

Hepatitis B virus transactivator X protein is not tumorigenic in transgenic mice

28 July 2018

1 reference

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Differential regulation of the hepatitis B virus surface gene promoters by a second viral enhancer

28 July 2018

1 reference

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HBx gene of hepatitis B virus induces liver cancer in transgenic mice

28 July 2018

1 reference

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The ubiquitous transcription factor Oct-1 and the liver-specific factor HNF-1 are both required to activate transcription of a hepatitis B virus promoter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192172

The role of envelope proteins in hepatitis B virus assembly

28 July 2018

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Production and effect of infectious Dane particles in transgenic mice

28 July 2018

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CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life

28 July 2018

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Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase. Implications for peroxisome proliferator-activated receptor alpha natural ligand metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Focus on hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Long-term expression of the hepatitis B virus core-e- and X-proteins does not cause pathologic changes in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Infectious hepatitis B virus variant defective in pre-S2 protein expression in a chronic carrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Non-sequencing molecular approaches to identify preS2-defective hepatitis B virus variants proved to be associated with severe liver diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Injection-mediated transposon transgenesis in Xenopus tropicalis and the identification of integration sites by modified extension primer tag selection (EPTS) linker-mediated PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Survival characteristics and age-adjusted disease incidences in C57BL/6 mice fed a commonly used cereal-based diet modulated by dietary restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Activating transcription factor 3 induces DNA synthesis and expression of cyclin D1 in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026240

Hepatocellular carcinoma results from chronic cyclin D1 overexpression in transgenic mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192172

Activation of hepatitis B virus S promoter by the viral large surface protein via induction of stress in the endoplasmic reticulum

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192172

Risk Factors for Hepatocellular Carcinoma among Patients with Chronic Liver Disease

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22022578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Standard karyotype of the mouse, Mus musculus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22022578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Karyotyping Mouse Cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22022578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0026240

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference