Diversity and complexity of HIV-1 drug resistance: a bioinformatics approach to predicting phenotype from genotype (Q34032267)

30 July 2017

title

Diversity and complexity of HIV-1 drug resistance: a bioinformatics approach to predicting phenotype from genotype (English)

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30 July 2017

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Thomas Lengauer

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30 July 2017

Niko Beerenwinkel

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Joachim Selbig

series ordinal

object named as

Joachim Selbig

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30 July 2017

Rolf Kaiser

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30 July 2017

Hauke Walter

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30 July 2017

Barbara Schmidt

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30 July 2017

Daniel Hoffmann

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30 July 2017

Klaus Korn

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30 July 2017

language of work or name

English

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publication date

1 June 2002

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Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

8271-8276

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Crystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: Insights into the mechanisms of drug resistance

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=123057

Human immunodeficiency virus type 1 reverse transcriptase and protease mutation search engine for queries

5 July 2018

1 reference

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Low level of cross-resistance to amprenavir (141W94) in samples from patients pretreated with other protease inhibitors

5 July 2018

1 reference

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Structural proteomics of an archaeon

5 July 2018

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HIV drug susceptibility and treatment response to mega-HAART regimen in patients from the Frankfurt HIV cohort

5 July 2018

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The relation between baseline HIV drug resistance and response to antiretroviral therapy: re-analysis of retrospective and prospective studies using a standardized data analysis plan.

5 July 2018

1 reference

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A mutation in human immunodeficiency virus type 1 protease, N88S, that causes in vitro hypersensitivity to amprenavir

5 July 2018

1 reference

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A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V

5 July 2018

1 reference

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A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance.

5 July 2018

1 reference

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Rapid, phenotypic HIV-1 drug sensitivity assay for protease and reverse transcriptase inhibitors

5 July 2018

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Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development

5 July 2018

1 reference

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Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome

5 July 2018

1 reference

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Managing resistance to anti-HIV drugs: an important consideration for effective disease management.

5 July 2018

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A rapid method for simultaneous detection of phenotypic resistance to inhibitors of protease and reverse transcriptase in recombinant human immunodeficiency virus type 1 isolates from patients treated with antiretroviral drugs

5 July 2018

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Neutralization sensitivity of cell culture-passaged simian immunodeficiency virus

5 July 2018

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Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase

5 July 2018

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Drug-resistance genotyping in HIV-1 therapy: the VIRADAPT randomised controlled trial.

5 July 2018

1 reference

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Simple algorithm derived from a geno-/phenotypic database to predict HIV-1 protease inhibitor resistance.

21 January 2018

1 reference

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Methods for investigation of the relationship between drug-susceptibility phenotype and human immunodeficiency virus type 1 genotype with applications to AIDS clinical trials group 333.

21 January 2018

1 reference

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Decision tree-based formation of consensus protein secondary structure prediction.

21 January 2018

1 reference

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Baseline HIV drug resistance profile predicts response to ritonavir-saquinavir protease inhibitor therapy in a community setting.

21 January 2018

1 reference

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Simplifying decision trees

21 January 2018

1 reference

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Phenotypic HIV-1 resistance correlates with treatment outcome of nelfinavir salvage therapy.

21 January 2018

1 reference

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Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy

29 October 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1073/PNAS.112177799

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journals/pnas/BeerenwinkelSWK02

30 July 2017

0 references

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DBLP Dataset 2021-01-02

28 January 2021

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30 July 2017

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