Lipid bodies in inflammatory cells: structure, function, and current imaging techniques. (Q34026238)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21430261%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

review article

1 reference

title

Lipid bodies in inflammatory cells: structure, function, and current imaging techniques (English)

1 reference

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26 January 2020

1 reference

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26 January 2020

1 reference

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26 January 2020

Heloisa D'Avila

1 reference

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26 January 2020

Hsiao-Ching Wan

series ordinal

1 reference

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26 January 2020

Ann M Dvorak

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26 January 2020

Peter F Weller

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26 January 2020

publication date

23 March 2011

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Journal of Histochemistry and Cytochemistry

26 January 2020

published in

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26 January 2020

volume

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26 January 2020

issue

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26 January 2020

page(s)

540-556

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Imaging lipid bodies within leukocytes with different light microscopy techniques.

26 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Lipid droplets lighting up: insights from live microscopy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Lipid droplets: a dynamic organelle moves into focus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Lipid droplets finally get a little R-E-S-P-E-C-T.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Contribution of macrophage migration inhibitory factor to the pathogenesis of dengue virus infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Live cell multicolor imaging of lipid droplets with a new dye, LD540.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Lipid droplets and hepatitis C virus infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Quantitative label-free imaging of lipid composition and packing of individual cellular lipid droplets using multiplex CARS microscopy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Acute heart inflammation: ultrastructural and functional aspects of macrophages elicited by Trypanosoma cruzi infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Deficiency of adipose differentiation-related protein impairs foam cell formation and protects against atherosclerosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Lipid homeostasis in macrophages - implications for atherosclerosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Chlamydia pneumoniae--induced macrophage foam cell formation is mediated by Toll-like receptor 2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Identification and characterization of associated with lipid droplet protein 1: A novel membrane-associated protein that resides on hepatic lipid droplets

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Leukocyte lipid bodies regulation and function: contribution to allergy and host defense

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Fixation and permeabilization protocol is critical for the immunolabeling of lipid droplet proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Single-cell Raman and fluorescence microscopy reveal the association of lipid bodies with phagosomes in leukocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

PAT family proteins pervade lipid droplet cores.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Role of PAT proteins in lipid metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

New views of cells in 3D: an introduction to electron tomography

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Electron microscope immunocytochemical localization of cyclooxygenase-1 and -2 in pseudopregnant rat corpus luteum during luteolysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Food vacuole-associated lipid bodies and heterogeneous lipid environments in the malaria parasite, Plasmodium falciparum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Vibrational imaging of lipid droplets in live fibroblast cells with coherent anti-Stokes Raman scattering microscopy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Deformation of lipid droplets in fixed samples

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

The biogenesis and functions of lipid bodies in animals, plants and microorganisms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

TIP47 associates with lipid droplets

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Mechanisms of platelet-activating factor-induced lipid body formation: requisite roles for 5-lipoxygenase and de novo protein synthesis in the compartmentalization of neutrophil lipids

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Migration of human inflammatory cells into the lung results in the remodeling of arachidonic acid into a triglyceride pool

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Application of Nile red, a fluorescent hydrophobic probe, for the detection of neutral lipid deposits in tissue sections: comparison with oil red O.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Cytoplasmic lipid bodies of neutrophils: formation induced by cis-unsaturated fatty acids and mediated by protein kinase C.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Mycobacterium bovis bacillus Calmette-Guérin infection induces TLR2-dependent peroxisome proliferator-activated receptor gamma expression and activation: functions in inflammation, lipid metabolism, and pathogenesis.

28 July 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Extranuclear lipid bodies, elicited by CCR3-mediated signaling pathways, are the sites of chemokine-enhanced leukotriene C4 production in eosinophils and basophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Eosinophil Lipid Bodies: Specific, Inducible Intracellular Sites for Enhanced Eicosanoid Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Mycobacterium bovis bacillus Calmette-Guérin induces TLR2-mediated formation of lipid bodies: intracellular domains for eicosanoid synthesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Neutrophils recruited to the site of Mycobacterium bovis BCG infection undergo apoptosis and modulate lipid body biogenesis and prostaglandin E production by macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Synergism between platelet-activating factor-like phospholipids and peroxisome proliferator-activated receptor gamma agonists generated during low density lipoprotein oxidation that induces lipid body formation in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Imaging lipid bodies in cells and tissues using third-harmonic generation microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Fixation Methods for the Study of Lipid Droplets by Immunofluorescence Microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Cytosolic phospholipase A2 participates with TNF-alpha in the induction of apoptosis of human macrophages infected with Mycobacterium tuberculosis H37Ra

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Mast cell secretory granules and lipid bodies contain the necessary machinery important for the in situ synthesis of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Prostaglandin endoperoxide synthase (cyclooxygenase): ultrastructural localization to nonmembrane-bound cytoplasmic lipid bodies in human eosinophils and 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Proteomic insights into an expanded cellular role for cytoplasmic lipid droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Schistosomal‐Derived Lysophosphatidylcholine Are Involved in Eosinophil Activation and Recruitment through Toll‐Like Receptor–2–Dependent Mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Modulation of lipid droplets by Mycobacterium leprae in Schwann cells: a putative mechanism for host lipid acquisition and bacterial survival in phagosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Leptin induces macrophage lipid body formation by a phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Macrophage lipid body induction by Chagas disease in vivo: putative intracellular domains for eicosanoid formation during infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Electron tomography and immunonanogold electron microscopy for investigating intracellular trafficking and secretion in human eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Trypanosoma cruzi: peripheral blood monocytes and heart macrophages in the resistance to acute experimental infection in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Cutting edge: prostaglandin D2 enhances leukotriene C4 synthesis by eosinophils during allergic inflammation: synergistic in vivo role of endogenous eotaxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Adipophilin expression is increased in symptomatic carotid atherosclerosis: correlation with red blood cells and cholesterol crystals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Lipid droplets as dynamic organelles connecting storage and efflux of lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Lipopolysaccharide-induced leukocyte lipid body formation in vivo: innate immunity elicited intracellular Loci involved in eicosanoid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

A CD36-dependent signaling cascade is necessary for macrophage foam cell formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

The role of prostaglandin E2 in the immunopathogenesis of experimental pulmonary tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Adipose differentiation-related protein: a gonadotropin- and prostaglandin-regulated protein in primate periovulatory follicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Lipid bodies in oxidized LDL-induced foam cells are leukotriene-synthesizing organelles: a MCP-1/CCL2 regulated phenomenon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Resistin increases lipid accumulation and CD36 expression in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1369%2F0022155411404073

Host cells: mobilizable lipid resources for the intracellular parasite Toxoplasma gondii.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Cross-Talk between Macrophage Migration Inhibitory Factor and Eotaxin in Allergic Eosinophil Activation Forms Leukotriene C4–Synthesizing Lipid Bodies

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Rat models to investigate host macrophage defense against Trypanosoma cruzi

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Lipid bodies: Structural markers of inflammatory macrophages in innate immunity

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201176

Endogenous platelet-activating factor is critically involved in effector functions of eosinophils stimulated with IL-5 or IgG

10 December 2018

1 reference

12 December 2020

Cytoplasmic lipid bodies in eosinophils: central roles in eicosanoid generation

1 reference

12 December 2020

Evolution of granulomas in lungs of mice infected aerogenically with Mycobacterium tuberculosis

1 reference

12 December 2020

Optimisation of oil red O staining permits combination with immunofluorescence and automated quantification of lipids

1 reference

12 December 2020

Leukocyte lipid bodies: inflammation-related organelles are rapidly detected by wet scanning electron microscopy

1 reference

12 December 2020

Monocyte Chemoattractant Protein-1/CC Chemokine Ligand 2 Controls Microtubule-Driven Biogenesis and Leukotriene B4-Synthesizing Function of Macrophage Lipid Bodies Elicited by Innate Immune Response

1 reference

12 December 2020

Global tuberculosis control: key findings from the December 2009 WHO report

1 reference

12 December 2020

Lipid bodies: cytoplasmic organelles important to arachidonate metabolism in macrophages and mast cells

1 reference

12 December 2020

Metabolism of 1-pyrenedecanoic acid and accumulation of neutral fluorescent lipids in cultured fibroblasts of multisystemic lipid storage myopathy

1 reference

12 December 2020

Release of tumor necrosis factor-alpha from macrophages. Enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleotides

1 reference

12 December 2020

Ultrastructural immunogold localization of prostaglandin endoperoxide synthase (cyclooxygenase) to non-membrane-bound cytoplasmic lipid bodies in human lung mast cells, alveolar macrophages, type II pneumocytes, and neutrophils

1 reference

12 December 2020

Ultrastructural immunogold localization of subcellular sites of TNF-α in colonic Crohn’s disease

1 reference

12 December 2020

Identifiers

DOI

10.1369/0022155411404073

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21430261%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21430261%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

21430261

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21430261%20AND%20SRC:MED&resulttype=core&format=json