The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R. (Q34009345)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11818541%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R (English)

1 reference

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G protein-coupled receptor

6 December 2019

main subject

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1 reference

1 reference

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6 December 2019

M Resnati

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6 December 2019

I Pallavicini

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6 December 2019

J M Wang

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6 December 2019

J Oppenheim

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6 December 2019

C N Serhan

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6 December 2019

F Blasi

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6 December 2019

language of work or name

English

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publication date

29 January 2002

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Proceedings of the National Academy of Sciences of the United States of America

6 December 2019

published in

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6 December 2019

volume

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issue

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6 December 2019

page(s)

1359-1364

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Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1.

6 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1

5 July 2018

1 reference

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Novel pathophysiological role of classical chemotactic peptide receptors and their communications with chemokine receptors.

5 July 2018

1 reference

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Urokinase receptor: a molecular organizer in cellular communication.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

5 July 2018

1 reference

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Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis

5 July 2018

1 reference

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The scent of a phagocyte: Advances on leukotriene b(4) receptors

5 July 2018

1 reference

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Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection

5 July 2018

1 reference

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Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation

5 July 2018

1 reference

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Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Chemoattractant receptor cross-desensitization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Exacerbation of antigen-induced arthritis in urokinase-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Regulation of integrin function by the urokinase receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Urokinase is required for the pulmonary inflammatory response to Cryptococcus neoformans. A murine transgenic model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: inhibition of CD11/18 expression by lipoxin A4-lipoxin A4 receptor interaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Serum level of soluble urokinase-type plasminogen activator receptor is a strong and independent predictor of survival in human immunodeficiency virus infection.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

uPA, uPAR, PAI-I: Key intersection of proteolytic, adhesive and chemotacfic highways?

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=122195

Plasma Urokinase Receptor Levels in Patients With Colorectal Cancer: Relationship to Prognosis

29 October 2018

1 reference

12 December 2020

Shedding and cleavage of the urokinase receptor (uPAR): identification and characterisation of uPAR fragments in vitro and in vivo

1 reference

12 December 2020

Clustering of urokinase receptors (uPAR; CD87) induces proinflammatory signaling in human polymorphonuclear neutrophils

1 reference

12 December 2020

Soluble urokinase receptor levels correlate with number of circulating tumor cells in acute myeloid leukemia and decrease rapidly during chemotherapy

1 reference

12 December 2020

Ligand interaction between urokinase-type plasminogen activator and its receptor probed with 8-anilino-1-naphthalenesulfonate. Evidence for a hydrophobic binding site exposed only on the intact receptor

1 reference

12 December 2020

A cleaved form of the receptor for urokinase-type plasminogen activator in invasive transplanted human and murine tumors

1 reference

12 December 2020

Cancer invasion and tissue remodeling: common themes in proteolytic matrix degradation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.022652999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11818541%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

0 references

1 reference

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6 December 2019

PubMed publication ID

11818541

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11818541%20AND%20SRC:MED&resulttype=core&format=json