Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging (Q34006053)

30 July 2017

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title

Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging (English)

1 reference

30 July 2017

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Ronald C Petersen

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30 July 2017

J Eric Ahlskog

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30 July 2017

Yonas E Geda

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30 July 2017

Neill R Graff-Radford

series ordinal

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30 July 2017

language of work or name

English

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publication date

1 September 2011

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30 July 2017

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

876-884

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30 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition

5 July 2018

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5 July 2018

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An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus

5 July 2018

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Insulin-like growth factor I interfaces with brain-derived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function

5 July 2018

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Exercise enhances learning and hippocampal neurogenesis in aged mice.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Brain-derived neurotrophic factor is reduced in Alzheimer's disease

5 July 2018

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5 July 2018

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BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

5 July 2018

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5 July 2018

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5 July 2018

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Voluntary exercise does not enhance long-term potentiation in the adolescent female dentate gyrus

29 October 2018

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29 October 2018

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29 October 2018

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Strength training does not influence serum brain-derived neurotrophic factor

29 October 2018

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29 October 2018

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Evidence for a release of brain-derived neurotrophic factor from the brain during exercise

29 October 2018

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29 October 2018

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Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men.

29 October 2018

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Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease

29 October 2018

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Effects of endurance exercise on ventral tegmental area neurons in the chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and probenecid-treated mice

29 October 2018

1 reference

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Effects of strength and endurance training on brain-derived neurotrophic factor and insulin-like growth factor 1 in humans

29 October 2018

1 reference

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Exercise training acts as a therapeutic strategy for reduction of the pathogenic phenotypes for Alzheimer's disease in an NSE/APPsw-transgenic model.

29 October 2018

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BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study.

29 October 2018

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Wheel-running in a transgenic mouse model of Alzheimer's disease: protection or symptom?

29 October 2018

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Walking or vitamin B for cognition in older adults with mild cognitive impairment? A randomised controlled trial

29 October 2018

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Effect of regular exercise on senile dementia patients

29 October 2018

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The effect of acute exercise on serum brain-derived neurotrophic factor levels and cognitive function

29 October 2018

1 reference

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Aerobic exercise training increases brain volume in aging humans

29 October 2018

1 reference

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The effects of forced exercise on hippocampal plasticity in the rat: A comparison of LTP, spatial- and non-spatial learning

29 October 2018

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Acute BDNF and cortisol response to low intensity exercise and following ramp incremental exercise to exhaustion in humans

29 October 2018

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Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease

29 October 2018

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Serum BDNF, TNF-alpha and IL-1beta levels in dementia patients: comparison between Alzheimer's disease and vascular dementia

29 October 2018

1 reference

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BDNF serum and CSF concentrations in Alzheimer's disease, normal pressure hydrocephalus and healthy controls

29 October 2018

1 reference

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Exercise differentially regulates synaptic proteins associated to the function of BDNF.

29 October 2018

1 reference

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Exercise-induced changes in dendritic structure and complexity in the adult hippocampal dentate gyrus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Effects of physical activity on cognitive functioning in middle age: evidence from the Whitehall II prospective cohort study

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

The relation between insulin-like growth factor I levels and cognition in healthy elderly: a meta-analysis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Exercise primes a molecular memory for brain-derived neurotrophic factor protein induction in the rat hippocampus

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Voluntary exercise alters the cytoarchitecture of the adult dentate gyrus by increasing cellular proliferation, dendritic complexity, and spine density

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Exercise induces BDNF and synapsin I to specific hippocampal subfields

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

VEGF is necessary for exercise-induced adult hippocampal neurogenesis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Basal serum levels and reactivity of nerve growth factor and brain-derived neurotrophic factor to standardized acute exercise in multiple sclerosis and controls

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Aerobic fitness reduces brain tissue loss in aging humans

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Effects of resistance training on insulin-like growth factor and its binding proteins in men and women aged 60 to 85.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Life span and synapses: will there be a primary senile dementia?

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Relationships between cortisol, dehydroepiandrosterone sulphate and insulin-like growth factor-I system in dementia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Effects of resistance training on insulin-like growth factor-I and IGF binding proteins.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Physical activity and risk of cognitive impairment and dementia in elderly persons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Circulating insulin-like growth factor I mediates effects of exercise on the brain.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Transport of brain-derived neurotrophic factor across the blood-brain barrier

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

The effects of resistance training on well-being and memory in elderly volunteers.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

The Impact of Resistance Exercise on the Cognitive Function of the Elderly

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258000

Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway

10 December 2018

1 reference

12 December 2020

1 reference

12 December 2020

Physical Activity and Public Health in Older Adults

1 reference

12 December 2020

Lack of exercise, via hindlimb suspension, impedes endogenous neurogenesis

1 reference

12 December 2020

Influence of exercise on serum brain-derived neurotrophic factor concentrations in healthy human subjects

1 reference

12 December 2020

Cardio-respiratory fitness, habitual physical activity and serum brain derived neurotrophic factor (BDNF) in men and women

1 reference

12 December 2020

Serum brain-derived neurotrophic factor response to aerobic exercise in multiple sclerosis

1 reference

12 December 2020

Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease

1 reference

12 December 2020

Decreased serum brain-derived neurotrophic factor in trained men

1 reference

12 December 2020

IGF-I and IGFBP-3 during continuous and interval exercise

1 reference

12 December 2020

The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis

1 reference

12 December 2020

Brief, high intensity exercise alters serum ghrelin and growth hormone concentrations but not IGF-I, IGF-II or IGF-I bioactivity

1 reference

12 December 2020

Acute effect of brief low- and high-intensity exercise on circulating insulin-like growth factor (IGF) I, II, and IGF-binding protein-3 and its proteolysis in young healthy men

1 reference

12 December 2020

Identifiers

DOI

10.4065/MCP.2011.0252

1 reference

30 July 2017

1 reference

30 July 2017

1 reference