Molecular docking studies on interaction of diverse retinol structures with human alcohol dehydrogenases predict a broad role in retinoid ligand synthesis (Q22010263)

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English	Molecular docking studies on interaction of diverse retinol structures with human alcohol dehydrogenases predict a broad role in retinoid ligand synthesis	scientific article

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scholarly article

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Molecular docking studies on interaction of diverse retinol structures with human alcohol dehydrogenases predict a broad role in retinoid ligand synthesis (English)

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Alcohol dehydrogenase 4 (class II), pi polypeptide

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GOA release 2020-03-11

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GOA release 2020-03-11

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based on heuristic

inferred from title

object named as

G Duester

2

author given names

G

author last names

Duester

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PubMed publication ID

7 February 2023

author name string

M H Foglio

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author given names

M H

author last names

Foglio

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PubMed publication ID

7 February 2023

language of work or name

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publication date

13 July 1999

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Biochimica et Biophysica Acta

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1432

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2

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239-50

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A human retinoic acid receptor which belongs to the family of nuclear receptors

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a receptor for the morphogen retinoic acid

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Physiological substrates for rat alcohol dehydrogenase classes: aldehydes of lipid peroxidation, omega-hydroxyfatty acids, and retinoids

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Catalytic efficiency of human alcohol dehydrogenases for retinol oxidation and retinal reduction.

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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cDNA sequence and catalytic properties of a chick embryo alcohol dehydrogenase that oxidizes retinol and 3beta,5alpha-hydroxysteroids

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Contribution to first-pass metabolism of ethanol and inhibition by ethanol for retinol oxidation in human alcohol dehydrogenase family--implications for etiology of fetal alcohol syndrome and alcohol-related diseases

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Retinoids, omega-hydroxyfatty acids and cytotoxic aldehydes as physiological substrates, and H2-receptor antagonists as pharmacological inhibitors, of human class IV alcohol dehydrogenase

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Effect of cellular retinol-binding protein on retinol oxidation by human class IV retinol/alcohol dehydrogenase and inhibition by ethanol

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Cloning of a cDNA for liver microsomal retinol dehydrogenase. A tissue-specific, short-chain alcohol dehydrogenase

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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The retinal pigment epithelial-specific 11-cis retinol dehydrogenase belongs to the family of short chain alcohol dehydrogenases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Identification and characterization of a stereospecific human enzyme that catalyzes 9-cis-retinol oxidation. A possible role in 9-cis-retinoic acid formation

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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The alcohol dehydrogenase system

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Purification and molecular properties of mouse alcohol dehydrogenase isozymes

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Human aldehyde dehydrogenase gene family.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The equilibrium between vitamin A alcohol and aldehyde in the presence of alcohol dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Class IV alcohol/retinol dehydrogenase localization in epidermal basal layer: potential site of retinoic acid synthesis during skin development

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Localization of class I and class IV alcohol dehydrogenases in mouse testis and epididymis: potential retinol dehydrogenases for endogenous retinoic acid synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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Regional Restriction of Alcohol/Retinol Dehydrogenases along the Mouse Gastrointestinal Epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Initiation of retinoid signaling in primitive streak mouse embryos: spatiotemporal expression patterns of receptors and metabolic enzymes for ligand synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Vitamin A in human skin: II Concentrations of carotene, retinol and dehydroretinol in various components of normal skin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Endogenous retinoids in the early avian embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation of 3,4-didehydroretinoic acid, a novel morphogenetic signal in the chick wing bud.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Polarizing activity and retinoid synthesis in the floor plate of the neural tube

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

All-trans 3,4-didehydroretinoic acid equals all-trans retinoic acid in support of chick neuronal development

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel isoenzyme of aldehyde dehydrogenase specifically involved in the biosynthesis of 9-cis and all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Placental transfer and developmental effects of 9-cis retinoic acid in mice.

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel retinoic acid receptor ligands in Xenopus embryos

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The retinoid ligand 4-oxo-retinoic acid is a highly active modulator of positional specification.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

cDNA Cloning and Characterization of a cis-Retinol/3α-Hydroxysterol Short-chain Dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The identification of a 9-cis retinol dehydrogenase in the mouse embryo reveals a pathway for synthesis of 9-cis retinoic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Three-dimensional structure of horse liver alcohol dehydrogenase at 2.4 Å resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of human beta 1 beta 1 alcohol dehydrogenase: catalytic effects of non-active-site substitutions

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of cod liver class I alcohol dehydrogenase: substrate pocket and structurally variable segments

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of human chi chi alcohol dehydrogenase: a glutathione-dependent formaldehyde dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression and kinetic characterization of recombinant human stomach alcohol dehydrogenase. Active-site amino acid sequence explains substrate specificity compared with liver isozymes

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Computational modeling of a putative fetal alcohol syndrome mechanism

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular modelling of human gastric alcohol dehydrogenase (class IV) and substrate docking: differences towards the classical liver enzyme (class I)

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-based strategies for drug design and discovery

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structures of holo and apo-cellular retinol-binding protein II

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Solvent-accessible surfaces of proteins and nucleic acids

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

An all atom force field for simulations of proteins and nucleic acids

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular dynamics simulations of alcohol dehydrogenase with a four- or five-coordinate catalytic zinc ion.

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Structures of horse liver alcohol dehydrogenase complexed with NAD+ and substituted benzyl alcohols

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https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900104-1

7 January 2021

based on heuristic

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10.1016/S0167-4838(99)00104-1

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