Rab interacting lysosomal protein (Q21122718)

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mammalian protein found in Homo sapiens

• rab-interacting lysosomal protein
• RILP

edit

Language	Label	Description	Also known as
English	Rab interacting lysosomal protein	mammalian protein found in Homo sapiens	rab-interacting lysosomal protein RILP

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q96NA2

part of

JNK/Rab-associated protein-1, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

RH1 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

RH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Rab interacting lysosomal protein, dimerization domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q96NA2

encoded by

RILP

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q96NA2

molecular function

dynein light intermediate chain binding

determination method or standard

IPI

1 reference

retrieved

27 March 2018

stated in

A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96NA2&geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

protein binding

determination method or standard

IPI

6 references

retrieved

8 April 2019

stated in

RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

retrieved

8 April 2019

stated in

Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

retrieved

8 April 2019

stated in

The Salmonella virulence protein SifA is a G protein antagonist

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

retrieved

8 April 2019

stated in

RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

retrieved

8 April 2019

stated in

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

retrieved

8 April 2019

stated in

RILP is required for the proper morphology and function of late endosomes

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

small GTPase binding

determination method or standard

IPI

1 reference

retrieved

27 March 2018

stated in

Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96NA2&geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

protein dimerization activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

small GTPase binding

determination method or standard

IBA

IPI

2 references

retrieved

8 April 2019

stated in

Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IBA

dynein light intermediate chain binding

determination method or standard

IBA

IPI

2 references

retrieved

8 April 2019

stated in

A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region

GOA

curator

FlyBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IPI

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IBA

cell component

endosome

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

late endosome

determination method or standard

NAS

IDA

3 references

retrieved

8 April 2019

stated in

Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

NAS

retrieved

8 April 2019

stated in

RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IDA

retrieved

8 April 2019

stated in

Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IDA

phagocytic vesicle membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

late endosome membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

lysosomal membrane

determination method or standard

NAS

TAS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

TAS

retrieved

8 April 2019

stated in

Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

NAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

lysosome

determination method or standard

IDA

IEA

2 references

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96NA2&geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

retrieved

27 March 2018

stated in

Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96NA2&geneProductId=UniProtKB:Q96NA2

determination method or standard

IDA

cytoplasmic vesicle

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

cytosol

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

ciliary basal body

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IBA

protein-containing complex

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

cytoplasm

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IBA

lysosome

determination method or standard

IBA

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

retrieved

8 April 2019

stated in

Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IBA

biological process

positive regulation of protein catabolic process

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

RILP is required for the proper morphology and function of late endosomes

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IMP

antigen processing and presentation of exogenous peptide antigen via MHC class II

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

TAS

endosome transport via multivesicular body sorting pathway

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IDA

negative regulation of protein catabolic process

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IDA

endosome to lysosome transport

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IMP

early endosome to late endosome transport

determination method or standard

IMP

1 reference

retrieved

27 March 2018

stated in

RILP is required for the proper morphology and function of late endosomes

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96NA2&geneProductId=UniProtKB:Q96NA2

determination method or standard

IMP

intralumenal vesicle formation

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

RILP is required for the proper morphology and function of late endosomes

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IMP

regulation of multivesicular body size

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IDA

protein transport

determination method or standard

NAS

IEA

2 references

retrieved

8 April 2019

stated in

Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes.

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

NAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IEA

cilium assembly

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IBA

early endosome to late endosome transport

determination method or standard

IBA

IMP

2 references

retrieved

8 April 2019

stated in

RILP is required for the proper morphology and function of late endosomes

GOA

curator

UniProt

UniProt protein ID

Q96NA2

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IMP

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96NA2

determination method or standard

IBA

has part(s)

JNK/Rab-associated protein-1, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q96NA2

RH2 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q96NA2

RH1 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q96NA2

Rab interacting lysosomal protein, dimerization domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q96NA2

Identifiers

RefSeq protein ID

NP_113618

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

83547

XP_005256868

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

83547

XP_016880684

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

83547

UniProt protein ID

Q96NA2

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q96NA2

Ensembl protein ID

ENSP00000301336

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000301336

ENSP00000459101

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000459101

ENSP00000481849

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000481849

ENSP00000488063

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000488063

PDB structure ID

1YHN

1 reference

stated in

UniProt

UniProt protein ID

Q96NA2

retrieved

9 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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