Forkhead box H1 (Q21097188)

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mammalian protein found in Homo sapiens

fast-2
FOXH1
TGF-beta/activin signal transducer
forkhead activin signal transducer-1
forkhead box protein H1
forkhead activin signal transducer 2
Fast-1
Forkhead activin signal transducer 1
hFAST-1

Language	Label	Description	Also known as
English	Forkhead box H1	mammalian protein found in Homo sapiens	fast-2 FOXH1 TGF-beta/activin signal transducer forkhead activin signal transducer-1 forkhead box protein H1 forkhead activin signal transducer 2 Fast-1 Forkhead activin signal transducer 1 hFAST-1

Statements

1 reference

13 November 2019

UniProt protein ID

winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75593

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75593

Fork head domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fork head domain conserved site 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

co-SMAD binding

determination method or standard

1 reference

8 April 2019

Modulation of androgen receptor transactivation by FoxH1. A newly identified androgen receptor corepressor

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

protein domain specific binding

determination method or standard

1 reference

8 April 2019

Characterization of human FAST-1, a TGF beta and activin signal transducer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

sequence-specific DNA binding

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Characterization of human FAST-1, a TGF beta and activin signal transducer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

androgen receptor binding

determination method or standard

1 reference

8 April 2019

Modulation of androgen receptor transactivation by FoxH1. A newly identified androgen receptor corepressor

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

DNA-binding transcription factor activity

determination method or standard

4 references

8 April 2019

Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

bHLH transcription factor binding

determination method or standard

1 reference

8 April 2019

HEB and E2A function as SMAD/FOXH1 cofactors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

protein binding

determination method or standard

5 references

8 April 2019

Oct25 represses transcription of nodal/activin target genes by interaction with signal transducers during Xenopus gastrulation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Characterization of human FAST-1, a TGF beta and activin signal transducer

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

HEB and E2A function as SMAD/FOXH1 cofactors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Modulation of androgen receptor transactivation by FoxH1. A newly identified androgen receptor corepressor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

determination method or standard

4 references

8 April 2019

Characterization of human FAST-1, a TGF beta and activin signal transducer

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Modulation of androgen receptor transactivation by FoxH1. A newly identified androgen receptor corepressor

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

determination method or standard

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75593&geneProductId=UniProtKB:O75593

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Modulation of androgen receptor transactivation by FoxH1. A newly identified androgen receptor corepressor

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Characterization of human FAST-1, a TGF beta and activin signal transducer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

biological process

ventricular trabecula myocardium morphogenesis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

anterior/posterior pattern specification

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

negative regulation of androgen receptor signaling pathway

determination method or standard

1 reference

8 April 2019

Modulation of androgen receptor transactivation by FoxH1. A newly identified androgen receptor corepressor

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

embryonic heart tube anterior/posterior pattern specification

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75593&geneProductId=UniProtKB:O75593

determination method or standard

outflow tract morphogenesis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry

determination method or standard

1 reference

8 April 2019

Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

axial mesoderm development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

cardiac right ventricle morphogenesis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

determination of left/right symmetry

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

secondary heart field specification

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

positive regulation of transcription, DNA-templated

determination method or standard

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Characterization of human FAST-1, a TGF beta and activin signal transducer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

regulation of transcription, DNA-templated

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

aorta morphogenesis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75593&geneProductId=UniProtKB:O75593

determination method or standard

negative regulation of intracellular estrogen receptor signaling pathway

determination method or standard

1 reference

8 April 2019

Modulation of androgen receptor transactivation by FoxH1. A newly identified androgen receptor corepressor

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

transforming growth factor beta receptor signaling pathway

determination method or standard

3 references

8 April 2019

Characterization of human FAST-1, a TGF beta and activin signal transducer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

3 references

8 April 2019

Homeoprotein DLX-1 interacts with Smad4 and blocks a signaling pathway from activin A in hematopoietic cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

8 April 2019

Characterization of human FAST-1, a TGF beta and activin signal transducer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

cellular response to cytokine stimulus

determination method or standard

1 reference

8 April 2019

Homeoprotein DLX-1 interacts with Smad4 and blocks a signaling pathway from activin A in hematopoietic cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

anatomical structure morphogenesis

determination method or standard

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75593&geneProductId=UniProtKB:O75593

determination method or standard

cell differentiation

determination method or standard

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75593&geneProductId=UniProtKB:O75593

determination method or standard

negative regulation of DNA-binding transcription factor activity

determination method or standard

1 reference

8 April 2019

Modulation of androgen receptor transactivation by FoxH1. A newly identified androgen receptor corepressor

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75593

determination method or standard

Fork head domain conserved site 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75593

Fork head domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75593

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000366534

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000366534

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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