Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism (Q29616720)

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21 December 2019

title

Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism (English)

2 references

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30 April 2017

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21 December 2019

1 reference

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21 December 2019

Nina M Haste

1 reference

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21 December 2019

Susan S Taylor

series ordinal

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21 December 2019

Lynn F Ten Eyck

series ordinal

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21 December 2019

language of work or name

1 reference

30 April 2017

publication date

9 November 2006

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

21 December 2019

number of pages

1 reference

based on heuristic

inferred from page(s)

published in

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21 December 2019

volume

103

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21 December 2019

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21 December 2019

page(s)

17783-17788

1 reference

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A Src-like inactive conformation in the abl tyrosine kinase domain

21 December 2019

cites work

1 reference

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Regulation of protein kinases; controlling activity through activation segment conformation

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Structural basis for the autoinhibition of c-Abl tyrosine kinase

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

The conformational plasticity of protein kinases

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Structure and regulation of the CDK5-p25(nck5a) complex

30 April 2017

1 reference

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Crystal structures of c-Src reveal features of its autoinhibitory mechanism

30 April 2017

1 reference

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Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

30 April 2017

1 reference

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Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

30 April 2017

1 reference

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Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

30 April 2017

1 reference

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Crystal structure of the tyrosine kinase domain of the human insulin receptor

30 April 2017

1 reference

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Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

30 April 2017

1 reference

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Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Dynamics of signaling by PKA.

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Hydrogen exchange solvent protection by an ATP analogue reveals conformational changes in ERK2 upon activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

The cAMP binding domain: an ancient signaling module

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Release of ADP from the catalytic subunit of protein kinase A: a molecular dynamics simulation study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Structural modes of stabilization of permissive phosphorylation sites in protein kinases: distinct strategies in Ser/Thr and Tyr kinases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

MAP kinases and CDKs: kinetic basis for catalytic activation

3 June 2018

1 reference

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Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?

3 June 2018

1 reference

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Structural aspects of protein kinase control-role of conformational flexibility

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Structural basis for control by phosphorylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

The protein kinase activity modulation sites: mechanisms for cellular regulation - targets for therapeutic intervention

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

NMR characterization of kinase p38 dynamics in free and ligand-bound forms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Catalytic independent functions of a protein kinase as revealed by a kinase-dead mutant: study of the Lys72His mutant of cAMP-dependent kinase

26 November 2018

1 reference

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Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1693824

Molecular motions of human cyclin-dependent kinase 2.

26 November 2018

1 reference

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BioLayout--an automatic graph layout algorithm for similarity visualization.

26 November 2018

1 reference

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26 November 2018

Identifiers

DOI

10.1073/PNAS.0607656103

3 references

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30 April 2017

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21 December 2019

ADS bibcode

2006PNAS..10317783K

0 references

1 reference

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3 references

30 April 2017

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21 December 2019

PubMed publication ID

3 references

30 April 2017

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