A critical and cell-autonomous role for MeCP2 in synaptic scaling up (Q28941201)

14 March 2017

title

A critical and cell-autonomous role for MeCP2 in synaptic scaling up (English)

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14 March 2017

Sacha B. Nelson

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Melissa P. Blackman

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14 March 2017

Biljana Djukic

series ordinal

1 reference

14 March 2017

Gina G. Turrigiano

series ordinal

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14 March 2017

language of work or name

English

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publication date

26 September 2012

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14 March 2017

published in

Journal of Neuroscience

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14 March 2017

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14 March 2017

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14 March 2017

page(s)

13529–13536

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The Rett syndrome protein MeCP2 regulates synaptic scaling

14 March 2017

cites work

1 reference

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16 March 2017

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16 March 2017

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MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number

16 March 2017

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Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome

16 March 2017

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MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions

16 March 2017

1 reference

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16 March 2017

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16 March 2017

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Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation

16 March 2017

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A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

16 March 2017

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Activity-dependent scaling of quantal amplitude in neocortical neurons

16 March 2017

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Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

16 March 2017

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The self-tuning neuron: synaptic scaling of excitatory synapses

7 April 2017

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Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation

7 April 2017

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Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

7 April 2017

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MeCP2 mutation results in compartment-specific reductions in dendritic branching and spine density in layer 5 motor cortical neurons of YFP-H mice

3 June 2018

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Mutation of MeCP2 alters transcriptional regulation of select immediate-early genes

3 June 2018

1 reference

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Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function

3 June 2018

1 reference

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The role of MeCP2 in the brain.

3 June 2018

1 reference

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Adult neural function requires MeCP2.

3 June 2018

1 reference

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PSD-95 and PSD-93 play critical but distinct roles in synaptic scaling up and down.

3 June 2018

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Experience-dependent retinogeniculate synapse remodeling is abnormal in MeCP2-deficient mice

3 June 2018

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Too Many Cooks? Intrinsic and Synaptic Homeostatic Mechanisms in Cortical Circuit Refinement

3 June 2018

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PICK1 loss of function occludes homeostatic synaptic scaling.

3 June 2018

1 reference

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Single-Cell Optogenetic Excitation Drives Homeostatic Synaptic Depression

3 June 2018

1 reference

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Unraveling mechanisms of homeostatic synaptic plasticity

3 June 2018

1 reference

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Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.

3 June 2018

1 reference

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Synaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in an RNA interference model of methyl-CpG-binding protein 2 deficiency

3 June 2018

1 reference

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Intact long-term potentiation but reduced connectivity between neocortical layer 5 pyramidal neurons in a mouse model of Rett syndrome

3 June 2018

1 reference

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Synaptic scaling requires the GluR2 subunit of the AMPA receptor.

3 June 2018

1 reference

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Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology

3 June 2018

1 reference

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Coordinated changes in dendritic arborization and synaptic strength during neural circuit development

3 June 2018

1 reference

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Severe congenital encephalopathy caused by MECP2 null mutations in males: central hypoxia and reduced neuronal dendritic structure.

3 June 2018

1 reference

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Multiple modes of network homeostasis in visual cortical layer 2/3.

3 June 2018

1 reference

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Rapid synaptic scaling induced by changes in postsynaptic firing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Persistence of experience-induced homeostatic synaptic plasticity through adulthood in superficial layers of mouse visual cortex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Temporal regulation of the expression locus of homeostatic plasticity.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Elevated methyl-CpG-binding protein 2 expression is acquired during postnatal human brain development and is correlated with alternative polyadenylation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Associations between MeCP2 mutations, X-chromosome inactivation, and phenotype

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Critical periods for experience-dependent synaptic scaling in visual cortex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Activity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

RNAi-induced down-regulation of Mecp2 expression in the rat brain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Potentiation of cortical inhibition by visual deprivation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

MeCP2-dependent transcriptional repression regulates excitatory neurotransmission

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Adaptation to synaptic inactivity in hippocampal neurons

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Postsynaptic expression of homeostatic plasticity at neocortical synapses.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Expression of MeCP2 in olfactory receptor neurons is developmentally regulated and occurs before synaptogenesis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3483036

Activity-dependent modulation of synaptic AMPA receptor accumulation

26 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23015442

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activity coregulates quantal AMPA and NMDA currents at neocortical synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/23015442

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.3077-12.2012

1 reference

1 reference

1 reference

1 reference