Human stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypes (Q28652313)

object named as

Vernice Jackson-Lewis

0 references

Rita Sattler

object named as

Rita Sattler

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Christopher E. Henderson

object named as

Christopher E Henderson

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author name string

Laurent Roybon

0 references

Nuno J Lamas

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Alejandro Garcia-Diaz

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Eun Ju Yang

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Yoon A Kim

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C Alan Kachel

0 references

Jeffrey D Rothstein

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Hynek Wichterle

Role of gap junction protein connexin43 in astrogliosis induced by brain injury

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language of work or name

English

0 references

publication date

12 September 2013

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0 references

0 references

0 references

1035-48

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cites work

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17 March 2017

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Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

17 March 2017

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7 April 2017

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7 April 2017

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Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue

7 April 2017

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Mechanisms underlying inflammation in neurodegeneration

7 April 2017

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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

7 April 2017

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Wnt signalling regulates adult hippocampal neurogenesis

7 April 2017

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Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

7 April 2017

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Reactive astrocytes secrete lcn2 to promote neuron death

7 April 2017

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Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.

3 June 2018

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Accelerated high-yield generation of limb-innervating motor neurons from human stem cells

3 June 2018

1 reference

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Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells

3 June 2018

1 reference

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Fgf-dependent glial cell bridges facilitate spinal cord regeneration in zebrafish.

3 June 2018

1 reference

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Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells

3 June 2018

1 reference

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Genomic analysis of reactive astrogliosis

3 June 2018

1 reference

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GFAP-independent inflammatory competence and trophic functions of astrocytes generated from murine embryonic stem cells.

3 June 2018

1 reference

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Glial molecular alterations with mouse brain development and aging: up-regulation of the Kir4.1 and aquaporin-4.

3 June 2018

1 reference

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Spatial and temporal activation of spinal glial cells: role of gliopathy in central neuropathic pain following spinal cord injury in rats

3 June 2018

1 reference

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Directed differentiation of functional astroglial subtypes from human pluripotent stem cells

3 June 2018

1 reference

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The Physical Basis of FGFR3 Response to fgf1 and fgf2

3 June 2018

1 reference

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Astrocytes are endogenous regulators of basal transmission at central synapses

3 June 2018

1 reference

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Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

3 June 2018

1 reference

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Efficient differentiation of human embryonic and induced pluripotent stem cells into functional astrocytes.

3 June 2018

1 reference

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Specification of transplantable astroglial subtypes from human pluripotent stem cells

3 June 2018

1 reference

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Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

3 June 2018

1 reference

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FOXO3a inhibits TNF-α- and IL-1β-induced astrocyte proliferation:Implication for reactive astrogliosis

3 June 2018

1 reference

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A functionally characterized test set of human induced pluripotent stem cells

3 June 2018

1 reference

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Astrocyte-neuron metabolic relationships: for better and for worse

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Molecular comparison of GLT1+ and ALDH1L1+ astrocytes in vivo in astroglial reporter mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Immature astrocytes promote CNS axonal regeneration when combined with chondroitinase ABC

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

The role of excitatory amino acid transporters in cerebral ischemia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Directed differentiation of human-induced pluripotent stem cells generates active motor neurons

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Astrocyte-mediated control of cerebral blood flow

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Glutamate transporters bring competition to the synapse.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Interleukin-6 (IL-6) production by astrocytes: autocrine regulation by IL-6 and the soluble IL-6 receptor.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Developmental neurobiology. The milieu is the message

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

A distinctive distribution of reactive astroglia in the precentral cortex in amyotrophic lateral sclerosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Gliogenesis in rat spinal cord: evidence for origin of astrocytes and oligodendrocytes from radial precursors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Differential expression of three gap junction proteins in developing and mature brain tissues

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Prominent expression of acidic fibroblast growth factor in motor and sensory neurons

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Efficient generation of astrocytes from human pluripotent stem cells in defined conditions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Expression of protease-activated receptor (PAR)-2, but not other PARs, is regulated by inflammatory cytokines in rat astrocytes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Astrocytes Display Complex and Localized Calcium Responses to Single-Neuron Stimulation in the Hippocampus

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

An FGF-responsive astrocyte precursor isolated from the neonatal forebrain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Contribution of human embryonic stem cells to mouse blastocysts

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Phenotypic and functional heterogeneity of GFAP-expressing cells in vitro: differential expression of LeX/CD15 by GFAP-expressing multipotent neural stem cells and non-neurogenic astrocytes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Specification of motoneurons from human embryonic stem cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Glial glutamate transporters and maturation of the mouse somatosensory cortex

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Functional changes of glial glutamate transporter GLT-1 during ischemia: an in vivo study in the hippocampal CA1 of normal mice and mutant mice lacking GLT-1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Cytokine, chemokine and growth factor gene profiling of cultured human astrocytes after exposure to proinflammatory stimuli

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Sequential specification of neurons and glia by developmentally regulated extracellular factors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Growth factors regulate the survival and fate of cells derived from human neurospheres.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Regulation of astrocyte GFAP expression by TGF-beta1 and FGF-2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229657

Astrocyte-associated fibronectin is critical for axonal regeneration in adult white matter

27 November 2018

1 reference

12 December 2020

A unique pattern of astrocytosis in the primary motor area in amyotrophic lateral sclerosis

1 reference

12 December 2020

Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis

1 reference

12 December 2020

Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: effect of in vitro differentiation on graft survival and teratoma formation

1 reference

12 December 2020

Fibroblast growth factor 2 regulates astrocyte differentiation in a region-specific manner in the hindbrain

1 reference

12 December 2020

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1523/JNEUROSCI.4178-07.2008

Identifiers

DOI

10.1016/J.CELREP.2013.06.021

1 reference

1 reference

1 reference

PubMed publication ID

23994478

1 reference