PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations (Q28587440)

31 January 2017

title

PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations (English)

1 reference

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

31 January 2017

main subject

1 reference

Presenilin 1

1 reference

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

1 reference

Glycogen synthase kinase 3 beta

1 reference

Phosphoinositide-3-kinase regulatory subunit 1

1 reference

Thymoma viral proto-oncogene 1

1 reference

Cadherin 1

1 reference

Cadherin 2

1 reference

Lia Baki

1 reference

31 January 2017

Junichi Shioi

1 reference

31 January 2017

Paul Wen

1 reference

31 January 2017

Zhiping Shao

1 reference

31 January 2017

Alexander Schwarzman

1 reference

31 January 2017

Miguel Gama-Sosa

1 reference

31 January 2017

Rachael Neve

1 reference

31 January 2017

Nikolaos K. Robakis

1 reference

31 January 2017

language of work or name

English

0 references

publication date

7 July 2004

1 reference

31 January 2017

1 reference

31 January 2017

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31 January 2017

1 reference

31 January 2017

page(s)

2586–2596

1 reference

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

31 January 2017

cites work

1 reference

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17 March 2017

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17 March 2017

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17 March 2017

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17 March 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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3 June 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation.

21 January 2018

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Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes

27 November 2018

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Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.

27 November 2018

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Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/15192701

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal

1 reference

https://pubmed.ncbi.nlm.nih.gov/15192701

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tau phosphorylation in cells transfected with wild-type or an Alzheimer's disease mutant Presenilin 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15192701

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7600251

1 reference

1 reference

1 reference

1 reference