RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development (Q28585313)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development (English)

2 references

PubMed

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json

Ras homolog family member H

20 December 2019

main subject

1 reference

Zeta-chain (TCR) associated protein kinase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Yi Gu

2 references

31 January 2017

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20 December 2019

Hee-Don Chae

2 references

PubMed

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Jamie E Siefring

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Aparna C Jasti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

David A Williams

1 reference

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20 December 2019

language of work or name

English

0 references

publication date

8 October 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

2 references

31 January 2017

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20 December 2019

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

2 references

31 January 2017

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20 December 2019

page(s)

1182-1190

1 reference

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Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

20 December 2019

cites work

1 reference

The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function

21 April 2017

1 reference

Essential role for ZAP-70 in both positive and negative selection of thymocytes

21 April 2017

1 reference

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 April 2017

1 reference

T cell receptor signaling precedes immunological synapse formation

21 April 2017

1 reference

Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck

21 April 2017

1 reference

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

21 April 2017

1 reference

Profound block in thymocyte development in mice lacking p56lck

21 April 2017

1 reference

Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation

21 April 2017

1 reference

Bcl11b is required for differentiation and survival of αβ T lymphocytes

21 April 2017

1 reference

Molecular genetics of T cell development

21 April 2017

1 reference

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

21 January 2018

1 reference

Selective events in T cell development

21 January 2018

1 reference

GTPases and T cell activation

21 January 2018

1 reference

RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration, and engraftment of hematopoietic progenitor cells

21 January 2018

1 reference

Structural features of hematopoiesis-specific RhoH/ARHH gene: high diversity of 5'-UTR in different hematopoietic lineages suggests a complex post-transcriptional regulation

21 January 2018

1 reference

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif

21 January 2018

1 reference

Signal transduction by the TCR for antigen

21 January 2018

1 reference

MAP-kinase signaling pathways in T cells

21 January 2018

1 reference

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

21 January 2018

1 reference

Cellular aspects of early T-cell development

21 January 2018

1 reference

Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells

21 January 2018

1 reference

Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

21 January 2018

1 reference

CD69 expression during selection and maturation of CD4+8+ thymocytes.

21 January 2018

1 reference

Molecular analysis of the antigen receptor of virus-specific cytotoxic T cells and identification of a new V alpha family

21 January 2018

1 reference

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

21 January 2018

1 reference

Antigen receptor tail clue.

21 January 2018

1 reference

SH2 domains: role, structure and implications for molecular medicine

21 January 2018

1 reference

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

21 January 2018

1 reference

CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity

21 January 2018

1 reference

Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells

21 January 2018

1 reference

Regulation of antigen receptor signal transduction by protein tyrosine kinases

21 January 2018

1 reference

Serine phosphorylation differentially affects RhoA binding to effectors: implications to NGF-induced neurite outgrowth

21 January 2018

1 reference

Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.

21 January 2018

1 reference

The GTPase Rho has a critical regulatory role in thymus development

21 January 2018

1 reference

Influence of multiplicity of infection and protein stability on retroviral vector-mediated gene expression in hematopoietic cells

21 January 2018

1 reference

Involvement of an ATP-Dependent Peptide Chaperone in Cross-Presentation After DNA Immunization

21 January 2018

1 reference

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

21 January 2018

1 reference

RhoH is required to maintain the integrin LFA-1 in a nonadhesive state on lymphocytes

21 January 2018

1 reference

7 January 2021

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

1 reference

7 January 2021

Defective recruitment and activation of ZAP-70 in common variable immunodeficiency patients with T cell defects

1 reference

7 January 2021

CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection

1 reference

7 January 2021

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

1 reference

7 January 2021

Role of the Guanosine Triphosphatase Rac2 in T Helper 1 Cell Differentiation

1 reference

7 January 2021

Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases

1 reference

7 January 2021

Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling

1 reference

7 January 2021

Optimization of fibronectin-assisted retroviral gene transfer into human CD34+ hematopoietic cells

1 reference

7 January 2021

Retrovirus-mediated gene transfer into T cells: 95% transduction efficiency without further in vitro selection

1 reference

7 January 2021

Identifiers

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

2 references

PubMed

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17028588%20AND%20SRC:MED&resulttype=core&format=json