Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (Q28578617)

31 January 2017

title

Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells (English)

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31 January 2017

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hepatocellular carcinoma

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Ki-Yong Kim

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31 January 2017

Byung-Chul Kim

series ordinal

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31 January 2017

Zhiheng Xu

series ordinal

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31 January 2017

Seong-Jin Kim

series ordinal

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31 January 2017

language of work or name

English

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publication date

9 July 2004

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

279

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31 January 2017

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31 January 2017

page(s)

29478–29484

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Transcriptional control by the TGF-beta/Smad signaling system

31 January 2017

cites work

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ICE-like protease (caspase) is involved in transforming growth factor beta1-mediated apoptosis in FaO rat hepatoma cell line

21 January 2018

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Cdc2 and Cdk2 kinase activated by transforming growth factor-beta1 trigger apoptosis through the phosphorylation of retinoblastoma protein in FaO hepatoma cells

21 January 2018

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Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells

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Caspase cleavage enhances the apoptosis-inducing effects of BAD.

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Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains

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Complete nucleotide sequence, expression, and chromosomal localisation of human mixed-lineage kinase 2

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Mixed-lineage kinase control of JNK and p38 MAPK pathways

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The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.

21 January 2018

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MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase

21 January 2018

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The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

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Molecular Cloning and Functional Expression of a cDNA Encoding a New Member of Mixed Lineage Protein Kinase from Human Brain

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Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation

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A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

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SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis

21 January 2018

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Zipper-mediated oligomerization of the mixed lineage kinase SPRK/MLK-3 is not required for its activation by the GTPase cdc 42 but Is necessary for its activation of the JNK pathway. Monomeric SPRK L410P does not catalyze the activating phosphorylat

21 January 2018

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Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line

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The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis

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Requirement of TGF-beta receptor-dependent activation of c-Jun N-terminal kinases (JNKs)/stress-activated protein kinases (Sapks) for TGF-beta up-regulation of the urokinase-type plasminogen activator receptor

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Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation

21 January 2018

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TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

21 January 2018

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Identification of in vivo phosphorylation sites of MLK3 by mass spectrometry and phosphopeptide mapping

21 January 2018

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Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors

21 January 2018

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

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Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase

21 January 2018

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Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy

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Extracellular signal-regulated kinase (ERK) activity is required for TPA-mediated inhibition of drug-induced apoptosis.

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21 January 2018

Identifiers

DOI

10.1074/JBC.M313947200

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017