Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells (Q28541550)

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English	Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells	scientific article

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instance of

scholarly article

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title

Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells (English)

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main subject

Human Induced Pluripotent Stem Cells

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based on heuristic

inferred from title

author

Tamihide Matsunaga

series ordinal

14

object named as

Tamihide Matsunaga

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Takahiro Iwao

series ordinal

2

object named as

Takahiro Iwao

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Yuki Kondo

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1

object named as

Yuki Kondo

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Sachimi Yoshihashi

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3

object named as

Sachimi Yoshihashi

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Kayo Mimori

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4

object named as

Kayo Mimori

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Ruri Ogihara

series ordinal

5

object named as

Ruri Ogihara

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Kiyoshi Nagata

series ordinal

6

object named as

Kiyoshi Nagata

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Kouichi Kurose

series ordinal

7

object named as

Kouichi Kurose

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Takuro Niwa

series ordinal

9

object named as

Takuro Niwa

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Katsunori Nakamura

series ordinal

13

object named as

Katsunori Nakamura

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author name string

Masayoshi Saito

series ordinal

8

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Takayoshi Suzuki

series ordinal

10

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Naoki Miyata

series ordinal

11

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Shigeru Ohmori

series ordinal

12

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language of work or name

English

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publication date

2014

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published in

PLOS One

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volume

9

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issue

8

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page(s)

e104010

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copyright license

Creative Commons Attribution 4.0 International

start time

1 August 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Molecular and therapeutic potential and toxicity of valproic acid

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PubMed Central

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

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HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics

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19 March 2017

In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9)

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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

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7 April 2017

An efficient method for differentiation of human induced pluripotent stem cells into hepatocyte-like cells retaining drug metabolizing activity

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Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly.

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29 September 2017

Differentiation of human induced pluripotent stem cells into functional enterocyte-like cells using a simple method

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29 September 2017

Identification of small molecules for human hepatocyte expansion and iPS differentiation

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29 September 2017

Modification of histone acetylation facilitates hepatic differentiation of human bone marrow mesenchymal stem cells

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PubMed Central

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29 September 2017

Rapid discovery of highly potent and selective inhibitors of histone deacetylase 8 using click chemistry to generate candidate libraries

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29 September 2017

Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction

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29 September 2017

The promotion of hepatic maturation of human pluripotent stem cells in 3D co-culture using type I collagen and Swiss 3T3 cell sheets

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29 September 2017

Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.

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Synapse microarray identification of small molecules that enhance synaptogenesis.

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29 September 2017

Hepatic endoderm differentiation from human embryonic stem cells.

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29 September 2017

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

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PubMed Central

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29 September 2017

Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells.

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PubMed Central

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29 September 2017

Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells

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PubMed Central

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29 September 2017

Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells

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Clinically relevant drug interactions with antiepileptic drugs

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Non-hydroxamate histone deacetylase inhibitors

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57 varieties: the human cytochromes P450.

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Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance

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29 September 2017

Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

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3 June 2018

Direct hepatic differentiation of mouse embryonic stem cells induced by valproic acid and cytokines.

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3 June 2018

Vascularized and functional human liver from an iPSC-derived organ bud transplant

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21 January 2018

Treatment of human embryonic stem cells with different combinations of priming and inducing factors toward definitive endoderm.

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21 January 2018

Efficient differentiation of hepatocytes from human embryonic stem cells exhibiting markers recapitulating liver development in vivo.

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21 January 2018

Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells

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retrieved

21 January 2018

Identifiers

DOI

10.1371/JOURNAL.PONE.0104010

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ADS bibcode

2014PLoSO...9j4010K

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PMC publication ID

4119015

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PubMed publication ID

25084468

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ResearchGate publication ID

264429930

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