Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism (Q28510829)

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

title

Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism (English)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

cytochrome P450, family 1, subfamily a, polypeptide 2

16 October 2019

main subject

1 reference

GOA release 2020-03-11

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

H C Liang

1 reference

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16 October 2019

H Li

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

J J Duffy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

S S Potter

1 reference

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16 October 2019

A Puga

1 reference

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16 October 2019

D W Nebert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

language of work or name

English

0 references

publication date

1 February 1996

1 reference

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16 October 2019

number of pages

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

page(s)

1671-1676

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

Expression of CYP1A1 and CYP1A2 genes in human liver

16 October 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Gsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survival

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

19 March 2017

1 reference

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

19 March 2017

2 references

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19 March 2017

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Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor

29 September 2017

1 reference

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cDNA cloning and structure of mouse putative Ah receptor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Drug-metabolizing enzymes in ligand-modulated transcription

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Cytochrome P450: evolution and functional diversity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

P450 genes: structure, evolution, and regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Cell-specific induction of mouse Cyp1a1 mRNA during development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Proposed role of drug-metabolizing enzymes: regulation of steady state levels of the ligands that effect growth, homeostasis, differentiation, and neuroendocrine functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

The murine Ah locus. Comparison of the complete cytochrome P1-450 and P3-450 cDNA nucleotide and amino acid sequences.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Developmental and tissue-specific differential regulation of the mouse dioxin-inducible P1-450 and P3-450 genes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Expression of the mouse P(1)450 gene during differentiation without foreign chemical stimulation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Transcriptional and post-transcriptional regulation of the genes encoding cytochromes P-450c and P-450d in vivo and in primary hepatocyte cultures.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Trout P450IA1: cDNA and deduced protein sequence, expression in liver, and evolutionary significance

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Drug metabolism. Growth signal pathways.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Elucidation of catalytic specificities of human cytochrome P450 and glutathione S-transferase enzymes and relevance to molecular epidemiology

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Cystic fibrosis in the mouse by targeted insertional mutagenesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Homeotic transformations and limb defects in Hox A11 mutant mice.

2 June 2018

1 reference

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Production of a severe cystic fibrosis mutation in mice by gene targeting

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

A severe phenotype in mice with a duplication of exon 3 in the cystic fibrosis locus.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40000

The aryl hydrocarbon hydroxylase (Ah) locus and a novel restriction-fragment length polymorphism (RFLP) are located on mouse chromosome 12

27 November 2018

1 reference

12 December 2020

The murine Ah locus: a new allele and mapping to chromosome 12

1 reference

12 December 2020

Expression of cytochromes P-450c and P-450d mRNAs in cultured rat hepatocytes. 3-Methylcholanthrene induction is regulated primarily at the post-transcriptional level

1 reference

12 December 2020

Caffeine as a probe for CYP1A2 activity: potential influence of renal factors on urinary phenotypic trait measurements

1 reference

12 December 2020

Genetic expression of aryl hydrocarbon hydroxylase induction. Presence or absence of association with zoxazolamine, diphenylhydantoin, and hexobarbital metabolism

1 reference

12 December 2020

Pharmacogenetics: an approach to understanding chemical and biologic aspects of cancer

1 reference

12 December 2020

Amino acid sequence of an analogous peptide from two forms of cytochrome P-450

1 reference

12 December 2020

Regional linkage analysis of the dioxin-inducible P-450 gene family on mouse chromosome 9

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.93.4.1671

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

0 references

release_t5wyj255r5aqjnrvprff4mrwlq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/t5wyj255r5aqjnrvprff4mrwlq

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8643688%20AND%20SRC:MED&resulttype=core&format=json