Targeting of K-Ras 4B by S-trans,trans-farnesyl thiosalicylic acid (Q28377435)

0 references

A Paz

0 references

R Haklai

0 references

D Marciano

0 references

A Cox

0 references

Y Kloog

Biochimica et Biophysica Acta

0 references

language of work or name

English

0 references

publication date

9 December 1999

0 references

published in

0 references

volume

1452

0 references

issue

0 references

page(s)

228-42

0 references

cites work

Proteins regulating Ras and its relatives

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Ras-dependent growth factor regulation of MEK kinase in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Function and regulation of ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

1 reference

7 January 2021

Ras signaling in tumor necrosis factor-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

1 reference

7 January 2021

p21ras: An oncoprotein functioning in growth factor-induced signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

p21ras is modified by a farnesyl isoprenoid

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

A CAAX or a CAAL motif and a second signal are sufficient for plasma membrane targeting of ras proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

All ras proteins are polyisoprenylated but only some are palmitoylated

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Lipid-binding characteristics of the polybasic carboxy-terminal sequence of K-ras4B

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Unexpectedly strong binding of a large metal ion (Bi3+) to human serum transferrin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Functional rafts in cell membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Reduction of caveolin and caveolae in oncogenically transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Farnesyl derivatives of rigid carboxylic acids-inhibitors of ras-dependent cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Selective Inhibition of Ras-dependent Cell Growth by Farnesylthiosalisylic Acid

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Dislodgment and Accelerated Degradation of Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Stringent structural requirements for anti-Ras activity of S-prenyl analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Polylysine and CVIM sequences of K-RasB dictate specificity of prenylation and confer resistance to benzodiazepine peptidomimetic in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Characterization of Ha-ras, N-ras, Ki-Ras4A, and Ki-Ras4B as in vitro substrates for farnesyl protein transferase and geranylgeranyl protein transferase type I

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Direct demonstration of geranylgeranylation and farnesylation of Ki-Ras in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

10 Mutation and analysis of prenylation signal sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

How MAP kinases are regulated

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

The Ras AntagonistS-Farnesylthiosalicylic Acid Induces Inhibition of MAPK Activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Evidence for a High Affinity, Saturable, Prenylation-dependent p21 Binding Site in Plasma Membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Membrane interactions of a constitutively active GFP-Ki-Ras 4B and their role in signaling. Evidence from lateral mobility studies.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

GM3-enriched Microdomain Involved in Cell Adhesion and Signal Transduction through Carbohydrate-Carbohydrate Interaction in Mouse Melanoma B16 Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021

Modulation of Ras and a-factor function by carboxyl-terminal proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2899%2900144-5

7 January 2021