Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons (Q28265834)

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12 February 2020

title

Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons (English)

1 reference

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12 February 2020

main subject

retrotrapezoid nucleus

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Paired-like homeobox 2b

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GOA release 2020-03-11

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

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12 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Carmen Birchmeier-Kohler

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object named as

Carmen Birchmeier

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Muriel Thoby-Brisson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Murielle Rallu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Karin Persson

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

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publication date

1 November 2009

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12 February 2020

published in

Journal of Neuroscience

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12 February 2020

volume

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issue

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12 February 2020

page(s)

14836-14846

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The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives

12 February 2020

cites work

1 reference

12 December 2020

Expression pattern of a Krox-20/Cre knock-in allele in the developing hindbrain, bones, and peripheral nervous system.

1 reference

12 December 2020

Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b.

1 reference

12 December 2020

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

1 reference

12 December 2020

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

1 reference

12 December 2020

Proprioceptor pathway development is dependent on Math1.

1 reference

12 December 2020

Chemosensitive neurons on the ventral medullary surface

1 reference

12 December 2020

Chemoreceptive mechanisms elucidated by studies of congenital central hypoventilation syndrome

1 reference

12 December 2020

Hindbrain patterning: Krox20 couples segmentation and specification of regional identity

1 reference

12 December 2020

The retrotrapezoid nucleus (RTN): local cytoarchitecture and afferent connections

1 reference

12 December 2020

Substance P-saporin lesion of neurons with NK1 receptors in one chemoreceptor site in rats decreases ventilation and chemosensitivity

1 reference

12 December 2020

A novel functional neuron group for respiratory rhythm generation in the ventral medulla.

1 reference

12 December 2020

Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in congenital central hypoventilation syndrome

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12 December 2020

Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors.

1 reference

12 December 2020

beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system

1 reference

12 December 2020

Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis

1 reference

12 December 2020

Respiratory control by ventral surface chemoreceptor neurons in rats

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12 December 2020

Homing in on the specific phenotype(s) of central respiratory chemoreceptors.

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12 December 2020

Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors

1 reference

12 December 2020

A developmental switch in the response of DRG neurons to ETS transcription factor signaling

1 reference

12 December 2020

Emergence of the pre-Bötzinger respiratory rhythm generator in the mouse embryo.

1 reference

12 December 2020

In pursuit (and discovery) of a genetic basis for congenital central hypoventilation syndrome

1 reference

12 December 2020

Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors

1 reference

12 December 2020

Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum

1 reference

12 December 2020

Point:Counterpoint: The parafacial respiratory group (pFRG)/pre-Botzinger complex (preBotC) is the primary site of respiratory rhythm generation in the mammal. Point: the PFRG is the primary site of respiratory rhythm generation in the mammal

1 reference

12 December 2020

Looking for inspiration: new perspectives on respiratory rhythm.

1 reference

12 December 2020

Expression of Phox2b by brainstem neurons involved in chemosensory integration in the adult rat.

1 reference

12 December 2020

Lbx1 acts as a selector gene in the fate determination of somatosensory and viscerosensory relay neurons in the hindbrain.

1 reference

12 December 2020

Cre activity causes widespread apoptosis and lethal anemia during embryonic development.

1 reference

12 December 2020

A human mutation in Phox2b causes lack of CO2 chemosensitivity, fatal central apnea, and specific loss of parafacial neurons.

1 reference

12 December 2020

Defects in breathing and thermoregulation in mice with near-complete absence of central serotonin neurons.

1 reference

12 December 2020

Selective lesion of retrotrapezoid Phox2b-expressing neurons raises the apnoeic threshold in rats

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12 December 2020

Central chemoreception is a complex system function that involves multiple brain stem sites

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12 December 2020

The 2008 Carl Ludwig Lecture: retrotrapezoid nucleus, CO2 homeostasis, and breathing automaticity

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12 December 2020

Central respiratory rhythmogenesis is abnormal in lbx1- deficient mice.

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12 December 2020

CO2-sensitive preinspiratory neurons of the parafacial respiratory group express Phox2b in the neonatal rat.

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12 December 2020

Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats

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12 December 2020

Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1.

1 reference

12 December 2020

Genetic identification of an embryonic parafacial oscillator coupling to the preBötzinger complex

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12 December 2020

PHOX2B in respiratory control: lessons from congenital central hypoventilation syndrome and its mouse models.

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12 December 2020

Brainstem projections to the major respiratory neuron populations in the medulla of the cat.

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12 December 2020

Are there serotonergic projections from raphe and retrotrapezoid nuclei to the ventral respiratory group in the rat?

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12 December 2020

A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system

1 reference

12 December 2020

Reorganization of pontine rhythmogenic neuronal networks in Krox-20 knockout mice

1 reference

12 December 2020

The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system

1 reference

12 December 2020

Differential expression of LIM homeobox genes among motor neuron subpopulations in the developing chick brain stem.

1 reference

12 December 2020

Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis

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12 December 2020

Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system

1 reference

12 December 2020

Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase

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12 December 2020

10.1523/JNEUROSCI.2623-09.2009

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

release_z6mik42qhvaqrcwhn24q6wqsu4

12 February 2020

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19940179

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19940179%20AND%20SRC:MED&resulttype=core&format=json