Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome (Q28241376)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1905793

Centrosomin Dmel_CG4832

1 reference

Centrosomal protein 190kD Dmel_CG6384

1 reference

Spindle assembly abnormal 6 Dmel_CG15524

1 reference

Spindle assembly abnormal 4 Dmel_CG10061

1 reference

Asterless Dmel_CG2919

1 reference

Author Correction: Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome

corrigendum / erratum

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Timothy L Megraw

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Steven P. Gygi

object named as

Steven P Gygi

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author name string

Jayachandran Gopalakrishnan

0 references

Vito Mennella

0 references

Stephanie Blachon

0 references

Bo Zhai

0 references

Andrew H Smith

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Daniela Nicastro

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David A Agard

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Tomer Avidor-Reiss

CEP152 is a genome maintenance protein disrupted in Seckel syndrome

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language of work or name

English

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publication date

21 June 2011

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published in

Nature Communications

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volume

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page(s)

359

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Asterless is a scaffold for the onset of centriole assembly

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Novel CENPJ mutation causes Seckel syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Drosophila asterless and vertebrate Cep152 Are orthologs essential for centriole duplication

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Plk4-induced centriole biogenesis in human cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Genes required for mitotic spindle assembly in Drosophila S2 cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Identification of a novel microtubule-destabilizing motif in CPAP that binds to tubulin heterodimers and inhibits microtubule assembly

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Centrioles, centrosomes, and cilia in health and disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

7 April 2017

Building the Centriole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Procentriole assembly revealed by cryo-electron tomography

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Drosophila Ana2 is a conserved centriole duplication factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Self-assembling SAS-6 multimer is a core centriole building block

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Pericentrin in cellular function and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Dimerization of CPAP orchestrates centrosome cohesion plasticity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Primary microcephaly: do all roads lead to Rome?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

CPAP is a cell-cycle regulated protein that controls centriole length

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Control of centriole length by CPAP and CP110.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Functional characterization of the microtubule-binding and -destabilizing domains of CPAP and d-SAS-4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the gamma-tubulin-mediated addition of centriolar microtubules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Control of daughter centriole formation by the pericentriolar material

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Revisiting the role of the mother centriole in centriole biogenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Centriole assembly in Caenorhabditis elegans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

29 September 2017

Flies without centrioles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Centriole assembly requires both centriolar and pericentriolar material proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

The Drosophila pericentrin-like protein is essential for cilia/flagella function, but appears to be dispensable for mitosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Recruitment of the gamma-tubulin ring complex to Drosophila salt-stripped centrosome scaffolds

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Spindle self-organization and cytokinesis during male meiosis in asterless mutants of Drosophila melanogaster.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

The disassembly and reassembly of functional centrosomes in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Three-dimensional structural characterization of centrosomes from early Drosophila embryos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Asterless is a centriolar protein required for centrosome function and embryo development in Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

DSAS-6 organizes a tube-like centriole precursor, and its absence suggests modularity in centriole assembly.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Asymmetric inheritance of mother versus daughter centrosome in stem cell division

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Higher order structure of the PCM adjacent to the centriole

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

The centrosome is a dynamic structure that ejects PCM flares.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1367

Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1367

SAS-4 is essential for centrosome duplication in C elegans and is recruited to daughter centrioles once per cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1367

SAS-4 is a C. elegans centriolar protein that controls centrosome size

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1367

A proximal centriole-like structure is present in Drosophila spermatids and can serve as a model to study centriole duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1367

Male gametogenesis without centrioles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1367

Reconstitution of centrosome microtubule nucleation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1367

The role of centrosomes and astral microtubules during asymmetric division of Drosophila neuroblasts.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

The homeotic target gene centrosomin encodes an essential centrosomal component

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677532

Astral microtubules monitor metaphase spindle alignment in fission yeast

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21694707

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

SAS-6 is a cartwheel protein that establishes the 9-fold symmetry of the centriole

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21694707

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS1367

1 reference

Dimensions Publication ID

ADS bibcode

2011NatCo...2..359G

0 references

1002852430

0 references

1 reference

1 reference

PubMed publication ID

21694707

1 reference