Exposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juice (Q28204828)

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Lisa P Gillen

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Joanne P Burke

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Ellen P Dorval

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Ed Pequignot

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Howard E Greenberg

The Journal of Clinical Pharmacology

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language of work or name

English

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publication date

August 2003

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published in

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volume

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issue

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page(s)

831-9

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cites work

Interaction of citrus juices with felodipine and nifedipine

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Acute effects of drinking grapefruit juice on the pharmacokinetics and dynamics of felodipine--and its potential clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Can grapefruit juice influence ethinylestradiol bioavailability?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Interaction between grapefruit juice and midazolam in humans*

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Grapefruit juice-simvastatin interaction: effect on serum concentrations of simvastatin, simvastatin acid, and HMG-CoA reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Trough concentrations of cyclosporine in blood following administration with grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine*

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Drug Interactions with Grapefruit Juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine*

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Noninvasive tests of CYP3A enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Clinical utility of breath tests for the assessment of hepatic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Effect of multiple doses of rifampin on the [14C N-methyl] erythromycin breath test in healthy male volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

The erythromycin breath test predicts the clearance of midazolam

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Characterization of midazolam metabolism using human hepatic microsomal fractions and hepatocytes in suspension obtained by perfusing whole human livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

First-pass metabolism of midazolam by the human intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

The area under the plasma concentration-time curve for oral midazolam is 400-fold larger during treatment with itraconazole than with rifampicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059

Rifampin drastically reduces plasma concentrations and effects of oral midazolam

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270003256059