Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway (Q28118756)

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway (English)

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

main subject

brain

0 references

Orthodenticle homeobox 2

1 reference

Forkhead box A2

1 reference

dopaminergic neuron differentiation

1 reference

Wingless-type MMTV integration site family, member 1

1 reference

LIM homeobox transcription factor 1 beta

1 reference

LIM homeobox transcription factor 1 alpha

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Sangmi Chung

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Amanda Leung

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Baek-Soo Han

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Mi-Yoon Chang

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Jung-Il Moon

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Chun-Hyung Kim

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Sunghoi Hong

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Kwang-Soo Kim

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

1 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

646-658

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age

13 February 2020

cites work

1 reference

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A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

20 March 2017

1 reference

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Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis

20 March 2017

1 reference

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Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain

20 March 2017

1 reference

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Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning

20 March 2017

1 reference

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Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2

20 March 2017

1 reference

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Otx2 regulates subtype specification and neurogenesis in the midbrain

20 March 2017

1 reference

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Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells

20 March 2017

1 reference

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Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner

20 March 2017

1 reference

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Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice

20 March 2017

1 reference

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Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo

20 March 2017

1 reference

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GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Parkinson's disease. First of two parts

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Foxa2: the rise and fall of dopamine neurons

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Markers and methods for cell sorting of human embryonic stem cell-derived neural cell populations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Serial analysis of chromatin occupancy identifies beta-catenin target genes in colorectal carcinoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

How to make a mesodiencephalic dopaminergic neuron

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Transcriptional control of midbrain dopaminergic neuron development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons.

29 September 2017

1 reference

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Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity.

29 September 2017

1 reference

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A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b.

29 September 2017

1 reference

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Functions of LIM-homeobox genes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Identification of intrinsic determinants of midbrain dopamine neurons

2 June 2018

1 reference

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Distinct regulators of Shh transcription in the floor plate and notochord indicate separate origins for these tissues in the mouse node.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Role of Lmx1b and Wnt1 in mesencephalon and metencephalon development.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

NKX2 gene expression in neuroectoderm but not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788512

A mitogen gradient of dorsal midline Wnts organizes growth in the CNS

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19951692

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STEM.2009.09.015

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951692%20AND%20SRC:MED&resulttype=core&format=json