eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core (Q27933768)

24852487

1 December 2016

title

eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core (English)

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24852487

Translation initiation factor eIF2 subunit beta YPL237W

1 December 2016

main subject

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Translation initiation factor eIF2 subunit gamma YER025W

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Translation initiation factor eIF2B subunit beta YLR291C

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Translation initiation factor eIF2B subunit alpha YKR026C

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Translation initiation factor eIF2 subunit alpha YJR007W

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Translation initiation factor eIF2B catalytic subunit epsilon YDR211W

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Translation initiation factor eIF2B subunit gamma YOR260W

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Translation initiation factor eIF2B subunit delta YGR083C

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Carla Schmidt

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Graham D Pavitt

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Martin D Jennings

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Carol V Robinson

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Dijana Matak-Vinković

series ordinal

object named as

Dijana Matak-Vinkovic

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author name string

Yuliya Gordiyenko

series ordinal

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language of work or name

English

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publication date

23 May 2014

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published in

Nature Communications

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Creative Commons Attribution 3.0 Unported

1 December 2016

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3902

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start time

23 May 2014

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation

29 September 2017

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Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2.

29 September 2017

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Structural modeling of heteromeric protein complexes from disassembly pathways and ion mobility-mass spectrometry.

29 September 2017

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Identification of intersubunit domain interactions within eukaryotic initiation factor (eIF) 2B, the nucleotide exchange factor for translation initiation

2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046112

Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046112

Phosphorylation of serine 51 in initiation factor 2 alpha (eIF2 alpha) promotes complex formation between eIF2 alpha(P) and eIF2B and causes inhibition in the guanine nucleotide exchange activity of eIF2B.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046112

Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon

2 June 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS4902

In vitro phosphorylation of initiation factor 2 alpha (aIF2 alpha) from hyperthermophilic archaeon Pyrococcus horikoshii OT3.

21 January 2018

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A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS4902

Collisional cooling of large ions in electrospray mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS4902

Catalysis of Guanine Nucleotide Exchange on eIF-2 by eIF-2B: Is it a Sequential or Substituted Enzyme Mechanism?

21 January 2018

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12 December 2020

Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry

1 reference

12 December 2020

The effect of Mg2+ and guanine nucleotide exchange factor on the binding of guanine nucleotides to eukaryotic initiation factor 2

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12 December 2020

Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation

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12 December 2020

Purification and kinetic analysis of eIF2B from Saccharomyces cerevisiae

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS4902

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Dimensions Publication ID

ADS bibcode

2014NatCo...5.3902G

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1032543976

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1 reference

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24852487

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