Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbalpha (Q27865238)

16 November 2016

title

Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbalpha (English)

1 reference

16 November 2016

Shree Joshi

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Nan Wu

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Mitchell A Lazar

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Lei Yin

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Elyisha A Hanniman

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta

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language of work or name

English

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publication date

15 September 2009

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1 reference

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2201-9

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cites work

1 reference

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Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

20 March 2017

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The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene

20 March 2017

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Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

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Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex

20 March 2017

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The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

20 March 2017

1 reference

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Coordinated transcription of key pathways in the mouse by the circadian clock

20 March 2017

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20 March 2017

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Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism

20 March 2017

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20 March 2017

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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

20 March 2017

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Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism

20 March 2017

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Ligand modulation of REV-ERBalpha function resets the peripheral circadian clock in a phasic manner

20 March 2017

1 reference

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Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha

20 March 2017

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Altered patterns of sleep and behavioral adaptability in NPAS2-deficient mice

20 March 2017

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

20 March 2017

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mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

7 April 2017

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Genome-wide analysis of estrogen receptor binding sites

7 April 2017

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Metabolic control through the PGC-1 family of transcription coactivators

7 April 2017

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Mammalian circadian biology: elucidating genome-wide levels of temporal organization

7 April 2017

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A transcription factor response element for gene expression during circadian night

7 April 2017

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Molecular analysis of mammalian circadian rhythms

7 April 2017

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Interacting molecular loops in the mammalian circadian clock

7 April 2017

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Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas

7 April 2017

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Minireview: Thyrotropin-releasing hormone and the thyroid hormone feedback mechanism

29 September 2017

1 reference

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Retinol saturase promotes adipogenesis and is downregulated in obesity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Minireview: the PGC-1 coactivator networks: chromatin-remodeling and mitochondrial energy metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

29 September 2017

1 reference

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The Year in Basic Science: nuclear receptors and coregulators

29 September 2017

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Nuclear receptors, metabolism, and the circadian clock.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Advances in measuring cellular bioenergetics using extracellular flux

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Nuclear hormone receptors for heme: REV-ERBalpha and REV-ERBbeta are ligand-regulated components of the mammalian clock.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Heme as a magnificent molecule with multiple missions: heme determines its own fate and governs cellular homeostasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Rev-erb alpha gives a time cue to metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

A sense of time: how molecular clocks organize metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Properties, entrainment, and physiological functions of mammalian peripheral oscillators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

The orphan nuclear receptor Rev-erb alpha regulates circadian expression of plasminogen activator inhibitor type 1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Going nuclear in metabolic and cardiovascular disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Estrogen receptor target gene: an evolving concept

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Heme, iron, and the mitochondrial decay of ageing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Orphan nuclear hormone receptor Rev-erbalpha regulates the human apolipoprotein CIII promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

A nuclear hormone receptor corepressor mediates transcriptional silencing by receptors with distinct repression domains.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Molecular determinants for cell specificity and glucocorticoid repression of the proopiomelanocortin gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Organization and expression of gonadotropin genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Oxidative hemoglobin denaturation and RBC destruction: the effect of heme on red cell membranes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Succinylacetone, a potent inhibitor of heme biosynthesis: Effect on cell growth, heme content and δ-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Relationship between circadian oscillations of Rev-erbalpha expression and intracellular levels of its ligand, heme.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Reciprocal regulation of haem biosynthesis and the circadian clock in mammals

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Functional adaptations of oxygen-transport proteins.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Mechanism of asbestos-mediated DNA damage: role of heme and heme proteins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1alpha

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Circadian rhythms: Something to cry about?

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751986

Lipid peroxidation and the degradation of cytochrome P-450 heme

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19710360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of heme depletion on growth, protein synthesis and respiration of murine erythroleukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19710360

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

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1 reference

16 November 2016

1 reference