Pathophysiology of the neurovascular unit: disease cause or consequence? (Q27690845)

Journal of Cerebral Blood Flow & Metabolism

published in

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1207-21

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Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

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Pericytes regulate the blood-brain barrier

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Structure and function of the blood-brain barrier

7 April 2017

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Oxygen sensing, homeostasis, and disease

7 April 2017

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Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampus

29 September 2017

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29 September 2017

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29 September 2017

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Immunotherapy for Alzheimer's disease: rational basis in ongoing clinical trials.

29 September 2017

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Engaging neuroscience to advance translational research in brain barrier biology.

29 September 2017

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Methods to Study Glycoproteins at the Blood-Brain Barrier Using Mass Spectrometry

29 September 2017

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Review: molecular genetics and pathology of hereditary small vessel diseases of the brain.

29 September 2017

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Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury

29 September 2017

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Molecular imaging of glioblastoma multiforme using anti-insulin-like growth factor-binding protein-7 single-domain antibodies

29 September 2017

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The neurovascular unit, matrix proteases, and innate inflammation

29 September 2017

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Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain

29 September 2017

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Vascular cognitive impairment: introduction

29 September 2017

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Low‐density lipoprotein receptor‐related protein‐1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β‐peptide elimination from the brain

29 September 2017

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The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia

29 September 2017

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Intact memory in TGF-β1 transgenic mice featuring chronic cerebrovascular deficit: recovery with pioglitazone

29 September 2017

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Genome-wide analysis of genetic loci associated with Alzheimer disease

29 September 2017

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Blood-brain barrier breakdown as a novel mechanism underlying cerebral hyperperfusion syndrome.

29 September 2017

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Migraine aura pathophysiology: the role of blood vessels and microembolisation

29 September 2017

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Differentiation of the brain vasculature: the answer came blowing by the Wnt.

29 September 2017

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Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease

29 September 2017

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Breaching the blood-brain barrier as a gate to psychiatric disorder

29 September 2017

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Blood-based biomarkers of microvascular pathology in Alzheimer's disease

29 September 2017

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Cortical spreading depression-new insights and persistent questions.

29 September 2017

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Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis?

29 September 2017

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Migraine and genetic and acquired vasculopathies

29 September 2017

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Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke

29 September 2017

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29 September 2017

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Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition

29 September 2017

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Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage

29 September 2017

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ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides.

29 September 2017

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Blood-brain barrier breakdown-inducing astrocytic transformation: novel targets for the prevention of epilepsy

29 September 2017

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Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain

29 September 2017

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Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease

29 September 2017

1 reference

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Endothelial signaling in paracellular and transcellular leukocyte transmigration

29 September 2017

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The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha

29 September 2017

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Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.

29 September 2017

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A role for leukocyte-endothelial adhesion mechanisms in epilepsy

29 September 2017

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Targeting extracellular matrix proteolysis for hemorrhagic complications of tPA stroke therapy

29 September 2017

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Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia.

29 September 2017

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The pathology of "vascular dementia": a critical update

29 September 2017

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Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease

29 September 2017

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Functional role of lipoprotein receptors in Alzheimer's disease

29 September 2017

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Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

29 September 2017

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29 September 2017

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Seizure-promoting effect of blood-brain barrier disruption

29 September 2017

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Molecular markers of extracellular matrix remodeling in glioblastoma vessels: microarray study of laser-captured glioblastoma vessels

29 September 2017

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Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy

29 September 2017

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TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis

29 September 2017

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Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system

29 September 2017

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29 September 2017

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Integrin-matrix interactions in the cerebral microvasculature

29 September 2017

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Perivascular nerves and the regulation of cerebrovascular tone

29 September 2017

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29 September 2017

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Cerebrovascular damage as a cause for Alzheimer's disease

29 September 2017

1 reference

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Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II.

29 September 2017

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Mini-review: Transendothelial migration of leukocytes: through the front door or around the side of the house?

29 September 2017

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Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex.

29 September 2017

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Endothelin-1 potently induces Leão's cortical spreading depression in vivo in the rat: a model for an endothelial trigger of migrainous aura?

29 September 2017

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Inflammatory mediators of cerebral endothelium: a role in ischemic brain inflammation.

29 September 2017

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Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

29 September 2017

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Plasma albumin is a potent trigger of calcium signals and DNA synthesis in astrocytes

29 September 2017

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Evidence for a role of dystroglycan regulating the membrane architecture of astroglial endfeet

29 September 2017

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A perfect storm: Converging paths of epilepsy and Alzheimer’s dementia intersect in the hippocampal formation

2 June 2018

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P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

2 June 2018

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Reduced cerebrovascular CO(2) reactivity in CADASIL: A transcranial Doppler sonography study

2 June 2018

1 reference

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Nitric oxide scavenging by hemoglobin or nitric oxide synthase inhibition by N-nitro-L-arginine induces cortical spreading ischemia when K+ is increased in the subarachnoid space

2 June 2018

1 reference

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Astrocyte-mediated induction of tight junctions in brain capillary endothelium: an efficient in vitro model

2 June 2018

1 reference

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The effect of bile salts on the permeability and ultrastructure of the perfused, energy-depleted, rat blood-brain barrier

2 June 2018

1 reference

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Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist

2 June 2018

1 reference

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Cortical changes in cerebral small vessel diseases: a 3D MRI study of cortical morphology in CADASIL.

27 November 2018

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Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults.

27 November 2018

1 reference

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Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects

27 November 2018

1 reference

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Blood-brain barrier disruption results in delayed functional and structural alterations in the rat neocortex

27 November 2018

1 reference

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Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures

27 November 2018

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IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.

27 November 2018

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Vasoconstrictive neurovascular coupling during focal ischemic depolarizations.

27 November 2018

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Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases

27 November 2018

1 reference

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Prediction of hemorrhagic transformation after thrombolytic therapy of clot embolism: an MRI investigation in rat brain

27 November 2018

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CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

27 November 2018

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Albumin elicits calcium signals from astrocytes in brain slices from neonatal rat cortex

27 November 2018

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beta-Amyloid-mediated vasoactivity and vascular endothelial damage.

27 November 2018

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Neurodegeneration and the neurovascular unit

27 November 2018

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12 December 2020

Spreading depression is not associated with neuronal injury in the normal brain

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12 December 2020

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

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12 December 2020

Endothelial tight junctions: permeable barriers of the vessel wall

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12 December 2020

Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system

1 reference

12 December 2020

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12 December 2020

Signal transduction by vascular endothelial growth factor receptors

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12 December 2020

Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FJCBFM.2012.25

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/JCBFM.2012.25

1 reference

1 reference

1 reference

PubMed publication ID

22395208

1 reference