Protein structure. Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism (Q27697681)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25635101%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Protein structure. Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism (English)

1 reference

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29 February 2020

0 references

0 references

1 reference

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29 February 2020

Fei Li

1 reference

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29 February 2020

Yi Zheng

series ordinal

1 reference

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29 February 2020

R Michael Garavito

series ordinal

1 reference

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29 February 2020

Shelagh Ferguson-Miller

series ordinal

1 reference

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29 February 2020

language of work or name

English

0 references

publication date

1 January 2015

1 reference

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29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25635101%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

347

1 reference

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29 February 2020

issue

6221

1 reference

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29 February 2020

page(s)

555-558

1 reference

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Structure of the mitochondrial translocator protein in complex with a diagnostic ligand

29 February 2020

cites work

1 reference

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Evolutionary origin of the mitochondrial cholesterol transport machinery reveals a universal mechanism of steroid hormone biosynthesis in animals

20 March 2017

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An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28

20 March 2017

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Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies

20 March 2017

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A mammalian mitochondrial drug receptor functions as a bacterial "oxygen" sensor

20 March 2017

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Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis

20 March 2017

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Translocator protein/peripheral benzodiazepine receptor is not required for steroid hormone biosynthesis

20 March 2017

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20 March 2017

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22 April 2017

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Features and development of Coot

22 April 2017

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UCSF Chimera--a visualization system for exploratory research and analysis

22 April 2017

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ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments

22 April 2017

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Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0

22 April 2017

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Characterization and modeling of the oligomeric state and ligand binding behavior of purified translocator protein 18 kDa from Rhodobacter sphaeroides

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125025

A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation

29 September 2017

1 reference

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The 18 kDa mitochondrial translocator protein (TSPO) prevents accumulation of protoporphyrin IX. Involvement of reactive oxygen species (ROS).

29 September 2017

1 reference

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The 18 kDa translocator protein (TSPO): a new perspective in mitochondrial biology

29 September 2017

1 reference

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Structural and functional evolution of the translocator protein (18 kDa).

29 September 2017

1 reference

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Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125025

Three-dimensional structure of TspO by electron cryomicroscopy of helical crystals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125025

Evaluation of translocator protein quantification as a tool for characterising macrophage burden in human carotid atherosclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125025

Protein-protein interactions in the membrane: sequence, structural, and biological motifs

29 September 2017

1 reference

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The origin of mitochondria in light of a fluid prokaryotic chromosome model.

29 September 2017

1 reference

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Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125025

Translocation mechanism of long sugar chains across the maltoporin membrane channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5125025

A novel mechanism for the regulation of photosynthesis gene expression by the TspO outer membrane protein of Rhodobacter sphaeroides 2.4.1.

29 September 2017

1 reference

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Peripheral-type benzodiazepine receptor (PBR) in human breast cancer: correlation of breast cancer cell aggressive phenotype with PBR expression, nuclear localization, and PBR-mediated cell proliferation and nuclear transport of cholesterol

29 September 2017

1 reference

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Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO).

29 September 2017

1 reference

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The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals

2 June 2018

1 reference

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Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression

21 January 2018

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In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding.

21 January 2018

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Flexible structure alignment by chaining aligned fragment pairs allowing twists

21 January 2018

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MUSTANG: a multiple structural alignment algorithm

21 January 2018

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A solution for the best rotation to relate two sets of vectors

21 January 2018

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Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding

21 January 2018

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Structural and functional study of reconstituted peripheral benzodiazepine receptor

21 January 2018

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Chemical catalysis by the translocator protein (18 kDa)

21 January 2018

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Evidence for complex binding profiles and species differences at the translocator protein (TSPO) (18 kDa).

21 January 2018

1 reference

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Evidence that variation in the peripheral benzodiazepine receptor (PBR) gene influences susceptibility to panic disorder

27 November 2018

1 reference

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Site-directed mutagenesis of the peripheral benzodiazepine receptor: identification of amino acids implicated in the binding site of Ro5-4864

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25635101

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25635101

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TspO of rhodobacter sphaeroides. A structural and functional model for the mammalian peripheral benzodiazepine receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25635101

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1260590

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25635101%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25635101%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

25635101

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25635101%20AND%20SRC:MED&resulttype=core&format=json