Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain (Q27675983)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23345433%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain (English)

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22 February 2020

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22 February 2020

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22 February 2020

1 reference

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22 February 2020

Penelope J Cross

1 reference

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22 February 2020

Timothy M Allison

series ordinal

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22 February 2020

language of work or name

English

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publication date

23 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23345433%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

22 February 2020

published in

1 reference

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22 February 2020

volume

110

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22 February 2020

issue

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22 February 2020

page(s)

2111-2116

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Structure of an Engineered β-Lactamase Maltose Binding Protein Fusion Protein: Insights into Heterotropic Allosteric Regulation

22 February 2020

cites work

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Structural analysis of a 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with an N-terminal chorismate mutase-like regulatory domain

20 March 2017

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Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery

20 March 2017

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Structural view of the regulatory subunit of aspartate kinase from Mycobacterium tuberculosis

20 March 2017

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Tyrosine Latching of a Regulatory Gate Affords Allosteric Control of Aromatic Amino Acid Biosynthesis

20 March 2017

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A new mode of dimerization of allosteric enzymes with ACT domains revealed by the crystal structure of the aspartate kinase from Cyanobacteria

20 March 2017

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20 March 2017

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20 March 2017

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Evolution of feedback-inhibited / barrel isoenzymes by gene duplication and a single mutation

20 March 2017

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Allosteric inhibition of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase alters the coordination of both substrates

20 March 2017

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Overview of the CCP4 suite and current developments

20 March 2017

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20 March 2017

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Phasercrystallographic software

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

20 March 2017

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Evolution of protein function by domain swapping

20 March 2017

2 references

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20 March 2017

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Gleaning non-trivial structural, functional and evolutionary information about proteins by iterative database searches

21 January 2018

1 reference

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Structure-based model of allostery predicts coupling between distant sites

7 April 2017

1 reference

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Allostery and the Monod-Wyman-Changeux model after 50 years

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568362

Structure and characterization of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Aeropyrum pernix

29 September 2017

1 reference

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Exploring and exploiting allostery: Models, evolution, and drug targeting

29 September 2017

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Structural and functional modularity of proteins in the de novo purine biosynthetic pathway.

29 September 2017

1 reference

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Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

29 September 2017

1 reference

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Allosteric regulation and catalysis emerge via a common route.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568362

Allostery: absence of a change in shape does not imply that allostery is not at play

29 September 2017

1 reference

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Amino acid biosynthesis: new architectures in allosteric enzymes

29 September 2017

1 reference

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Intrinsic dynamics of enzymes in the unbound state and relation to allosteric regulation

29 September 2017

1 reference

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The ACT domain: a small molecule binding domain and its role as a common regulatory element

29 September 2017

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Dynamically driven protein allostery.

29 September 2017

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The changing landscape of protein allostery

29 September 2017

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Directed evolution of protein switches and their application to the creation of ligand-binding proteins.

29 September 2017

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A new progressive-iterative algorithm for multiple structure alignment.

29 September 2017

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Allosteric mechanisms of signal transduction

29 September 2017

1 reference

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Allosteric mechanisms in ACT domain containing enzymes involved in amino acid metabolism.

29 September 2017

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Crystal structure of the reaction complex of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Thermotoga maritima refines the catalytic mechanism and indicates a new mechanism of allosteric regulation

29 September 2017

1 reference

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Creation of an allosteric enzyme by domain insertion.

29 September 2017

1 reference

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Design of generic biosensors based on green fluorescent proteins with allosteric sites by directed evolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568362

Unusual fatty acid compositions of the hyperthermophilic archaeon Pyrococcus furiosus and the bacterium Thermotoga maritima

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568362

NMR characterization of an engineered domain fusion between maltose binding protein and TEM1 beta-lactamase provides insight into its structure and allosteric mechanism.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568362

Surface sites for engineering allosteric control in proteins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3568362

Reconciling the "old" and "new" views of protein allostery: a molecular simulation study of chemotaxis Y protein (CheY).

2 June 2018

1 reference

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Searching distant homologs of the regulatory ACT domain in phenylalanine hydroxylase

21 January 2018

1 reference

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New insights into the evolutionary links relating to the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase subfamilies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1217923110

Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1217923110

CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1217923110

Design and evolution of new catalytic activity with an existing protein scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1217923110

Expression, purification, and characterization of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Pyrococcus furiosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1217923110

21 January 2018

Identifiers

DOI

10.1073/PNAS.1217923110

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23345433%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

ADS bibcode

2013PNAS..110.2111C

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23345433%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

23345433

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23345433%20AND%20SRC:MED&resulttype=core&format=json